Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Lapatinib | 10 | uM | 9 | 625.00 | 186.95 | 137.00 | 3089.00 | 0.0444 | -0.0740 |
MCF 10A | Lapatinib | 0.0033113 | uM | 9 | 625.00 | 186.95 | 3173.00 | 3089.00 | 1.0272 | 1.0133 |
MCF 10A | Linsitinib | 0.1 | uM | 9 | 625.00 | 186.95 | 2751.00 | 3089.00 | 0.8906 | 0.9435 |
MCF 10A | Lapatinib | 0.031623 | uM | 9 | 625.00 | 186.95 | 2775.00 | 3089.00 | 0.8984 | 0.9477 |
MCF 10A | 17-AAG | 0.031623 | uM | 9 | 625.00 | 186.95 | 140.00 | 3089.00 | 0.0453 | -0.0690 |
MCF 10A | 0 | uM | 9 | 625.00 | 186.95 | 2615.00 | 3089.00 | 0.8466 | 0.9193 | |
MCF 10A | 0 | uM | 9 | 1250.00 | 369.45 | 7539.00 | 6979.13 | 1.0802 | 1.0367 | |
MCF 10A | 0 | uM | 9 | 1250.00 | 369.45 | 6958.00 | 6979.13 | 0.9970 | 0.9986 | |
MCF 10A | Erlotinib | 0.0033113 | uM | 9 | 1250.00 | 369.45 | 7235.00 | 6979.13 | 1.0367 | 1.0171 |
MCF 10A | 17-AAG | 0.001 | uM | 9 | 1250.00 | 369.45 | 6589.00 | 6979.13 | 0.9441 | 0.9731 |
MCF 10A | 17-AAG | 0.000066069 | uM | 9 | 1250.00 | 369.45 | 8285.00 | 6979.13 | 1.1871 | 1.0826 |
MCF 10A | Linsitinib | 3.1623 | uM | 9 | 1250.00 | 369.45 | 2534.00 | 6979.13 | 0.3631 | 0.5749 |
MCF 10A | Erlotinib | 19.9526 | uM | 9 | 1250.00 | 369.45 | 430.00 | 6979.13 | 0.0616 | 0.0364 |
MCF 10A | Lapatinib | 0.1 | uM | 9 | 1250.00 | 369.45 | 7036.00 | 6979.13 | 1.0081 | 1.0038 |
MCF 10A | Lapatinib | 0.0016596 | uM | 9 | 1250.00 | 369.45 | 7998.00 | 6979.13 | 1.1460 | 1.0653 |
MCF 10A | 0 | uM | 9 | 1250.00 | 369.45 | 9031.00 | 6979.13 | 1.2940 | 1.1254 | |
MCF 10A | 17-AAG | 0.1 | uM | 9 | 1250.00 | 369.45 | 331.00 | 6979.13 | 0.0474 | -0.0256 |
MCF 10A | Erlotinib | 0.1 | uM | 9 | 1250.00 | 369.45 | 7645.00 | 6979.13 | 1.0954 | 1.0435 |
MCF 10A | Lapatinib | 0.31623 | uM | 9 | 1250.00 | 369.45 | 9405.00 | 6979.13 | 1.3476 | 1.1458 |
MCF 10A | Linsitinib | 0.31623 | uM | 9 | 1250.00 | 369.45 | 6239.00 | 6979.13 | 0.8940 | 0.9478 |
MCF 10A | Lapatinib | 0.01 | uM | 9 | 1250.00 | 369.45 | 7517.00 | 6979.13 | 1.0771 | 1.0353 |
MCF 10A | Linsitinib | 0.031623 | uM | 9 | 1250.00 | 369.45 | 7403.00 | 6979.13 | 1.0607 | 1.0280 |
MCF 10A | Erlotinib | 0.031623 | uM | 9 | 1250.00 | 369.45 | 7352.00 | 6979.13 | 1.0534 | 1.0247 |
MCF 10A | Erlotinib | 1 | uM | 9 | 1250.00 | 369.45 | 955.00 | 6979.13 | 0.1368 | 0.2511 |
MCF 10A | 17-AAG | 0.000302 | uM | 9 | 1250.00 | 369.45 | 6943.00 | 6979.13 | 0.9948 | 0.9976 |