Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | 17-AAG | 0.01 | uM | 8 | 1250.00 | 514.42 | 3352.00 | 9185.75 | 0.3649 | 0.5695 |
MCF 10A | Lapatinib | 0.031623 | uM | 8 | 1250.00 | 514.42 | 8601.00 | 9185.75 | 0.9363 | 0.9686 |
MCF 10A | Lapatinib | 0.0033113 | uM | 8 | 1250.00 | 514.42 | 8606.00 | 9185.75 | 0.9369 | 0.9689 |
MCF 10A | 17-AAG | 0.1 | uM | 8 | 1250.00 | 514.42 | 324.00 | 9185.75 | 0.0353 | -0.1052 |
MCF 10A | Linsitinib | 0.0033113 | uM | 8 | 1250.00 | 514.42 | 9429.00 | 9185.75 | 1.0265 | 1.0126 |
MCF 10A | Linsitinib | 3.1623 | uM | 8 | 1250.00 | 514.42 | 2468.00 | 9185.75 | 0.2687 | 0.4581 |
MCF 10A | Erlotinib | 0.0033113 | uM | 8 | 1250.00 | 514.42 | 9180.00 | 9185.75 | 0.9994 | 0.9997 |
MCF 10A | Lapatinib | 1 | uM | 8 | 1250.00 | 514.42 | 6836.00 | 9185.75 | 0.7442 | 0.8628 |
MCF 10A | 0 | uM | 8 | 1250.00 | 514.42 | 9086.00 | 9185.75 | 0.9891 | 0.9948 | |
MCF 10A | 0 | uM | 8 | 1250.00 | 514.42 | 8135.00 | 9185.75 | 0.8856 | 0.9424 | |
MCF 10A | 0 | uM | 8 | 2500.00 | 1235.42 | 12789.00 | 11524.50 | 1.1097 | 1.0657 | |
MCF 10A | 0 | uM | 8 | 2500.00 | 1235.42 | 11513.00 | 11524.50 | 0.9990 | 0.9994 | |
MCF 10A | Linsitinib | 0.1 | uM | 8 | 2500.00 | 1235.42 | 11726.00 | 11524.50 | 1.0175 | 1.0108 |
MCF 10A | Lapatinib | 3.1623 | uM | 8 | 2500.00 | 1235.42 | 7379.00 | 11524.50 | 0.6403 | 0.7415 |
MCF 10A | Linsitinib | 10 | uM | 8 | 2500.00 | 1235.42 | 4927.00 | 11524.50 | 0.4275 | 0.5363 |
MCF 10A | Erlotinib | 0.1 | uM | 8 | 2500.00 | 1235.42 | 11850.00 | 11524.50 | 1.0282 | 1.0174 |
MCF 10A | Erlotinib | 19.9526 | uM | 8 | 2500.00 | 1235.42 | 1579.00 | 11524.50 | 0.1370 | 0.0791 |
MCF 10A | Erlotinib | 1 | uM | 8 | 2500.00 | 1235.42 | 2207.00 | 11524.50 | 0.1915 | 0.1973 |
MCF 10A | 17-AAG | 0.0031623 | uM | 8 | 2500.00 | 1235.42 | 11535.00 | 11524.50 | 1.0009 | 1.0006 |
MCF 10A | 0 | uM | 8 | 2500.00 | 1235.42 | 11603.00 | 11524.50 | 1.0068 | 1.0042 | |
MCF 10A | Linsitinib | 1 | uM | 8 | 2500.00 | 1235.42 | 8428.00 | 11524.50 | 0.7313 | 0.8149 |
MCF 10A | Erlotinib | 0.031623 | uM | 8 | 2500.00 | 1235.42 | 12026.00 | 11524.50 | 1.0435 | 1.0266 |
MCF 10A | Lapatinib | 0.31623 | uM | 8 | 2500.00 | 1235.42 | 11725.00 | 11524.50 | 1.0174 | 1.0107 |
MCF 10A | 17-AAG | 0.0001 | uM | 8 | 2500.00 | 1235.42 | 11861.00 | 11524.50 | 1.0292 | 1.0179 |
MCF 10A | 0 | uM | 8 | 2500.00 | 1235.42 | 11549.00 | 11524.50 | 1.0021 | 1.0013 |