Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 1 of 3: Cell count and normalized growth rate inhibition values. - Dataset (ID:20256)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Etoposide | 0.1 | uM | 6 | 1250.00 | 531.21 | 6151.00 | 9860.25 | 0.6238 | 0.7881 |
MCF 10A | NVP-TAE684 | 0.031623 | uM | 6 | 1250.00 | 531.21 | 9387.00 | 9860.25 | 0.9520 | 0.9768 |
MCF 10A | 0 | uM | 6 | 1250.00 | 531.21 | 9796.00 | 9860.25 | 0.9935 | 0.9969 | |
MCF 10A | 0 | uM | 6 | 1250.00 | 531.21 | 9675.00 | 9860.25 | 0.9812 | 0.9910 | |
MCF 10A | 0 | uM | 6 | 1250.00 | 531.21 | 10050.00 | 9860.25 | 1.0192 | 1.0091 | |
MCF 10A | 0 | uM | 6 | 1250.00 | 531.21 | 9887.00 | 9860.25 | 1.0027 | 1.0013 | |
MCF 10A | PLX-4720 | 19.9526 | uM | 6 | 1250.00 | 531.21 | 3437.00 | 9860.25 | 0.3486 | 0.5575 |
MCF 10A | Nilotinib | 3.1623 | uM | 6 | 1250.00 | 531.21 | 9566.00 | 9860.25 | 0.9702 | 0.9857 |
MCF 10A | Etoposide | 0.0033113 | uM | 6 | 1250.00 | 531.21 | 9949.00 | 9860.25 | 1.0090 | 1.0043 |
MCF 10A | Etoposide | 0.031623 | uM | 6 | 1250.00 | 531.21 | 8111.00 | 9860.25 | 0.8226 | 0.9094 |
MCF 10A | PLX-4720 | 0.031623 | uM | 6 | 1250.00 | 531.21 | 10424.00 | 9860.25 | 1.0572 | 1.0266 |
MCF 10A | Nilotinib | 0.31623 | uM | 6 | 1250.00 | 531.21 | 10347.00 | 9860.25 | 1.0494 | 1.0230 |
MCF 10A | NVP-TAE684 | 0.0033113 | uM | 6 | 1250.00 | 531.21 | 10684.00 | 9860.25 | 1.0835 | 1.0384 |
MCF 10A | PLX-4720 | 0.1 | uM | 6 | 1250.00 | 531.21 | 10477.00 | 9860.25 | 1.0625 | 1.0290 |
MCF 10A | NVP-TAE684 | 0.1 | uM | 6 | 1250.00 | 531.21 | 8416.00 | 9860.25 | 0.8535 | 0.9262 |
MCF 10A | NVP-TAE684 | 0.01 | uM | 6 | 1250.00 | 531.21 | 10297.00 | 9860.25 | 1.0443 | 1.0207 |
MCF 10A | 0 | uM | 6 | 1250.00 | 531.21 | 10927.00 | 9860.25 | 1.1082 | 1.0494 | |
MCF 10A | Nilotinib | 0.01 | uM | 6 | 1250.00 | 531.21 | 10235.00 | 9860.25 | 1.0380 | 1.0178 |
MCF 10A | 0 | uM | 6 | 1250.00 | 531.21 | 10567.00 | 9860.25 | 1.0717 | 1.0331 | |
MCF 10A | NVP-TAE684 | 0.31623 | uM | 6 | 1250.00 | 531.21 | 7333.00 | 9860.25 | 0.7437 | 0.8643 |
MCF 10A | Etoposide | 0.01 | uM | 6 | 1250.00 | 531.21 | 9299.00 | 9860.25 | 0.9431 | 0.9724 |
MCF 10A | Etoposide | 1 | uM | 6 | 1250.00 | 531.21 | 1020.00 | 9860.25 | 0.1035 | 0.1674 |
MCF 10A | PLX-4720 | 10 | uM | 6 | 1250.00 | 531.21 | 6610.00 | 9860.25 | 0.6704 | 0.8189 |
MCF 10A | Etoposide | 10 | uM | 6 | 1250.00 | 531.21 | 508.00 | 9860.25 | 0.0515 | -0.0105 |
MCF 10A | Nilotinib | 0.0033113 | uM | 6 | 1250.00 | 531.21 | 9706.00 | 9860.25 | 0.9844 | 0.9925 |