LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|
SK-BR-3 | Lapatinib | 0.04 | uM | LJP6 | 0.4156 | 0.0102 | 0.0194 | 0.0535 |
SK-BR-3 | Lapatinib | 0.12 | uM | LJP6 | 0.4013 | 0.0208 | -0.0065 | 0.0414 |
SK-BR-3 | Lapatinib | 0.37 | uM | LJP6 | 0.3974 | 0.0125 | -0.0149 | 0.0595 |
SK-BR-3 | Lapatinib | 1.11 | uM | LJP6 | 0.4030 | 0.0158 | -0.0045 | 0.0678 |
SK-BR-3 | Lapatinib | 3.33 | uM | LJP6 | 0.4076 | 0.0076 | 0.0032 | 0.0750 |
SK-BR-3 | Lapatinib | 10 | uM | LJP6 | 0.4766 | 0.0259 | 0.1333 | 0.0201 |
SK-BR-3 | Sirolimus | 0.04 | uM | LJP6 | 0.6708 | 0.0052 | 0.4695 | 0.0399 |
SK-BR-3 | Sirolimus | 0.12 | uM | LJP6 | 0.6586 | 0.0110 | 0.4489 | 0.0324 |
SK-BR-3 | Sirolimus | 0.37 | uM | LJP6 | 0.6357 | 0.0202 | 0.4052 | 0.0710 |
SK-BR-3 | Sirolimus | 1.11 | uM | LJP6 | 0.6255 | 0.0145 | 0.3894 | 0.0522 |
SK-BR-3 | Sirolimus | 3.33 | uM | LJP6 | 0.6104 | 0.0166 | 0.3657 | 0.0475 |
SK-BR-3 | Sirolimus | 10 | uM | LJP6 | 0.6035 | 0.0019 | 0.3530 | 0.0586 |
SK-BR-3 | ZSTK474 | 0.04 | uM | LJP6 | 0.8544 | 0.0439 | 0.7826 | 0.0505 |
SK-BR-3 | ZSTK474 | 0.12 | uM | LJP6 | 0.6589 | 0.0495 | 0.4602 | 0.0349 |
SK-BR-3 | ZSTK474 | 0.37 | uM | LJP6 | 0.4927 | 0.0132 | 0.1609 | 0.0582 |
SK-BR-3 | ZSTK474 | 1.11 | uM | LJP6 | 0.4192 | 0.0065 | 0.0252 | 0.0703 |
SK-BR-3 | ZSTK474 | 3.33 | uM | LJP6 | 0.3927 | 0.0091 | -0.0251 | 0.0854 |
SK-BR-3 | ZSTK474 | 10 | uM | LJP6 | 0.3893 | 0.0127 | -0.0310 | 0.0765 |
SK-BR-3 | BX-912 | 0.04 | uM | LJP5 | 0.8176 | 0.0364 | 0.7237 | 0.0595 |
SK-BR-3 | BX-912 | 0.12 | uM | LJP5 | 0.8086 | 0.0463 | 0.7192 | 0.0515 |
SK-BR-3 | BX-912 | 0.37 | uM | LJP5 | 0.4822 | 0.0911 | 0.1747 | 0.1112 |
SK-BR-3 | BX-912 | 1.11 | uM | LJP5 | 0.3521 | 0.0090 | -0.0702 | 0.0459 |
SK-BR-3 | BX-912 | 3.33 | uM | LJP5 | 0.3669 | 0.0164 | -0.0412 | 0.0308 |
SK-BR-3 | BX-912 | 10 | uM | LJP5 | 0.3725 | 0.0231 | -0.0312 | 0.0513 |
SK-BR-3 | Selumetinib | 0.04 | uM | LJP6 | 1.0915 | 0.0101 | 1.1386 | 0.0009 |