LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Normalized Growth Rate Inhibition Value Standard Error of the Mean for Normalized Growth Rate Inhibition Value
SK-BR-3 Lapatinib
0.04
uM
LJP6
0.4156 0.0102 0.0194 0.0535
SK-BR-3 Lapatinib
0.12
uM
LJP6
0.4013 0.0208 -0.0065 0.0414
SK-BR-3 Lapatinib
0.37
uM
LJP6
0.3974 0.0125 -0.0149 0.0595
SK-BR-3 Lapatinib
1.11
uM
LJP6
0.4030 0.0158 -0.0045 0.0678
SK-BR-3 Lapatinib
3.33
uM
LJP6
0.4076 0.0076 0.0032 0.0750
SK-BR-3 Lapatinib
10
uM
LJP6
0.4766 0.0259 0.1333 0.0201
SK-BR-3 Sirolimus
0.04
uM
LJP6
0.6708 0.0052 0.4695 0.0399
SK-BR-3 Sirolimus
0.12
uM
LJP6
0.6586 0.0110 0.4489 0.0324
SK-BR-3 Sirolimus
0.37
uM
LJP6
0.6357 0.0202 0.4052 0.0710
SK-BR-3 Sirolimus
1.11
uM
LJP6
0.6255 0.0145 0.3894 0.0522
SK-BR-3 Sirolimus
3.33
uM
LJP6
0.6104 0.0166 0.3657 0.0475
SK-BR-3 Sirolimus
10
uM
LJP6
0.6035 0.0019 0.3530 0.0586
SK-BR-3 ZSTK474
0.04
uM
LJP6
0.8544 0.0439 0.7826 0.0505
SK-BR-3 ZSTK474
0.12
uM
LJP6
0.6589 0.0495 0.4602 0.0349
SK-BR-3 ZSTK474
0.37
uM
LJP6
0.4927 0.0132 0.1609 0.0582
SK-BR-3 ZSTK474
1.11
uM
LJP6
0.4192 0.0065 0.0252 0.0703
SK-BR-3 ZSTK474
3.33
uM
LJP6
0.3927 0.0091 -0.0251 0.0854
SK-BR-3 ZSTK474
10
uM
LJP6
0.3893 0.0127 -0.0310 0.0765
SK-BR-3 BX-912
0.04
uM
LJP5
0.8176 0.0364 0.7237 0.0595
SK-BR-3 BX-912
0.12
uM
LJP5
0.8086 0.0463 0.7192 0.0515
SK-BR-3 BX-912
0.37
uM
LJP5
0.4822 0.0911 0.1747 0.1112
SK-BR-3 BX-912
1.11
uM
LJP5
0.3521 0.0090 -0.0702 0.0459
SK-BR-3 BX-912
3.33
uM
LJP5
0.3669 0.0164 -0.0412 0.0308
SK-BR-3 BX-912
10
uM
LJP5
0.3725 0.0231 -0.0312 0.0513
SK-BR-3 Selumetinib
0.04
uM
LJP6
1.0915 0.0101 1.1386 0.0009