LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 14 of 15: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20251)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Mean Relative Cell Count | Standard Error of the Mean for Relative Cell Count | Mean Normalized Growth Rate Inhibition Value | Standard Error of the Mean for Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A | GSK1059615 | 0.04 | uM | LJP5 | 1.0058 | 0.0207 | 1.0056 | 0.0111 |
| MCF 10A | GSK1059615 | 0.04 | uM | LJP6 | 0.9375 | 0.0574 | 0.9678 | 0.0280 |
| MCF 10A | GSK1059615 | 0.12 | uM | LJP5 | 0.8823 | 0.0785 | 0.9350 | 0.0390 |
| MCF 10A | GSK1059615 | 0.12 | uM | LJP6 | 0.7449 | 0.1336 | 0.8384 | 0.0778 |
| MCF 10A | GSK1059615 | 0.37 | uM | LJP5 | 0.4789 | 0.1234 | 0.6083 | 0.0839 |
| MCF 10A | GSK1059615 | 0.37 | uM | LJP6 | 0.4937 | 0.1540 | 0.6067 | 0.1275 |
| MCF 10A | GSK1059615 | 1.11 | uM | LJP5 | 0.1424 | 0.0511 | 0.1081 | 0.0400 |
| MCF 10A | GSK1059615 | 1.11 | uM | LJP6 | 0.1711 | 0.0579 | 0.1772 | 0.0417 |
| MCF 10A | GSK1059615 | 3.33 | uM | LJP5 | 0.0771 | 0.0252 | -0.0743 | 0.0116 |
| MCF 10A | GSK1059615 | 3.33 | uM | LJP6 | 0.0982 | 0.0421 | -0.0107 | 0.0408 |
| MCF 10A | GSK1059615 | 10 | uM | LJP5 | 0.0685 | 0.0324 | -0.1209 | 0.0382 |
| MCF 10A | GSK1059615 | 10 | uM | LJP6 | 0.0700 | 0.0322 | -0.1096 | 0.0376 |
| MCF 10A | Brivanib | 0.04 | uM | LJP5 | 0.9828 | 0.0204 | 0.9922 | 0.0098 |
| MCF 10A | Brivanib | 0.12 | uM | LJP5 | 0.9579 | 0.0284 | 0.9772 | 0.0133 |
| MCF 10A | Brivanib | 0.37 | uM | LJP5 | 0.9435 | 0.0230 | 0.9689 | 0.0090 |
| MCF 10A | Brivanib | 1.11 | uM | LJP5 | 0.8091 | 0.0548 | 0.8833 | 0.0247 |
| MCF 10A | Brivanib | 3.33 | uM | LJP5 | 0.6165 | 0.0847 | 0.7401 | 0.0410 |
| MCF 10A | Brivanib | 10 | uM | LJP5 | 0.2427 | 0.0609 | 0.3159 | 0.0249 |
| MCF 10A | CHIR-99021 | 0.04 | uM | LJP6 | 1.0181 | 0.0347 | 1.0132 | 0.0185 |
| MCF 10A | CHIR-99021 | 0.12 | uM | LJP6 | 1.0019 | 0.0442 | 1.0056 | 0.0235 |
| MCF 10A | CHIR-99021 | 0.37 | uM | LJP6 | 0.9844 | 0.0766 | 0.9975 | 0.0402 |
| MCF 10A | CHIR-99021 | 1.11 | uM | LJP6 | 0.9062 | 0.1299 | 0.9516 | 0.0717 |
| MCF 10A | CHIR-99021 | 3.33 | uM | LJP6 | 0.8284 | 0.1223 | 0.9002 | 0.0667 |
| MCF 10A | CHIR-99021 | 10 | uM | LJP6 | 0.6932 | 0.1255 | 0.7993 | 0.0735 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 1.0720 | 0.0181 | 1.0386 | 0.0044 |