LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 AZD 5438
10
uM
LJP6
 72
hr
 1209 697 4012 0.1736 -0.2739
MCF7 Pelitinib
0.04
uM
LJP5
 72
hr
 1209 4399 4203 1.0469 1.0515
MCF7 Pelitinib
0.12
uM
LJP5
 72
hr
 1209 4182 4203 0.9942 0.9924
MCF7 Pelitinib
0.37
uM
LJP5
 72
hr
 1209 3818 4203 0.9100 0.8984
MCF7 Pelitinib
1.11
uM
LJP5
 72
hr
 1209 2812 4203 0.6699 0.6000
MCF7 Pelitinib
3.33
uM
LJP5
 72
hr
 1209 1741 4203 0.4143 0.2239
MCF7 Pelitinib
10
uM
LJP5
 72
hr
 1209 849 4203 0.2031 -0.1788
MCF7 Luminespib
0.04
uM
LJP5
 72
hr
 1209 1245 4203 0.2967 0.0163
MCF7 Luminespib
0.12
uM
LJP5
 72
hr
 1209 1240 4203 0.2956 0.0141
MCF7 Luminespib
0.37
uM
LJP5
 72
hr
 1209 1235 4203 0.2949 0.0123
MCF7 Luminespib
1.11
uM
LJP5
 72
hr
 1209 1244 4203 0.2967 0.0152
MCF7 Luminespib
3.33
uM
LJP5
 72
hr
 1209 1297 4203 0.3089 0.0392
MCF7 Luminespib
10
uM
LJP5
 72
hr
 1209 1189 4203 0.2834 -0.0094
MCF7 AZD8330
0.04
uM
LJP5
 72
hr
 1209 2264 4203 0.5397 0.4182
MCF7 AZD8330
0.12
uM
LJP5
 72
hr
 1209 2154 4203 0.5130 0.3789
MCF7 AZD8330
0.37
uM
LJP5
 72
hr
 1209 2162 4203 0.5151 0.3822
MCF7 AZD8330
1.11
uM
LJP5
 72
hr
 1209 2091 4203 0.4975 0.3548
MCF7 AZD8330
3.33
uM
LJP5
 72
hr
 1209 2276 4203 0.5422 0.4221
MCF7 AZD8330
10
uM
LJP5
 72
hr
 1209 2370 4203 0.5652 0.4550
MCF7 TGX221
0.04
uM
LJP5
 72
hr
 1209 3847 4203 0.9152 0.9034
MCF7 TGX221
0.12
uM
LJP5
 72
hr
 1209 3699 4203 0.8792 0.8598
MCF7 TGX221
0.37
uM
LJP5
 72
hr
 1209 4044 4203 0.9619 0.9566
MCF7 TGX221
1.11
uM
LJP5
 72
hr
 1209 4008 4203 0.9549 0.9498
MCF7 TGX221
3.33
uM
LJP5
 72
hr
 1209 4072 4203 0.9709 0.9684
MCF7 TGX221
10
uM
LJP5
 72
hr
 1209 3243 4203 0.7735 0.7340