LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 Afatinib
1.11
uM
LJP6
 72
hr
 1097 3152 3673 0.8581 0.8317
SK-BR-3 Afatinib
1.11
uM
LJP6
 72
hr
 1401 1574 4168 0.3776 0.0762
BT-20 Afatinib
3.33
uM
LJP6
 72
hr
 1097 3253 3673 0.8856 0.8654
MDA-MB-231 Afatinib
3.33
uM
LJP6
 72
hr
 1235 2749 4405 0.6241 0.5463
MCF7 Afatinib
1.11
uM
LJP6
 72
hr
 1209 2817 4012 0.7008 0.6263
Hs 578T Afatinib
0.37
uM
LJP6
 72
hr
 658 3611 3761 0.9601 0.9678
MCF 10A Afatinib
0.04
uM
LJP6
 72
hr
 962 1713 10692 0.1603 0.1807
MDA-MB-231 Afatinib
0.12
uM
LJP6
 72
hr
 1235 4078 4405 0.9259 0.9175
SK-BR-3 Afatinib
3.33
uM
LJP6
 72
hr
 1401 1550 4168 0.3716 0.0641
Hs 578T Afatinib
0.12
uM
LJP6
 72
hr
 658 3670 3761 0.9759 0.9806
Hs 578T Afatinib
0.04
uM
LJP6
 72
hr
 658 3556 3761 0.9457 0.9560
MCF7 Afatinib
0.04
uM
LJP6
 72
hr
 1209 3665 4012 0.9147 0.9003
MDA-MB-231 Afatinib
0.04
uM
LJP6
 72
hr
 1235 4254 4405 0.9654 0.9608
SK-BR-3 Afatinib
0.04
uM
LJP6
 72
hr
 1401 1437 4168 0.3450 0.0161
MCF7 Afatinib
0.12
uM
LJP6
 72
hr
 1209 3666 4012 0.9160 0.9019
SK-BR-3 Afatinib
0.12
uM
LJP6
 72
hr
 1401 1416 4168 0.3400 0.0066
MDA-MB-231 Afatinib
1.11
uM
LJP6
 72
hr
 1235 2739 4405 0.6225 0.5442
MDA-MB-231 Afatinib
0.37
uM
LJP6
 72
hr
 1235 3577 4405 0.8130 0.7868
MCF7 Afatinib
10
uM
LJP6
 72
hr
 1209 922 4012 0.2304 -0.1451
MCF7 Afatinib
0.37
uM
LJP6
 72
hr
 1209 3723 4012 0.9287 0.9168
BT-20 Afatinib
10
uM
LJP6
 72
hr
 1097 816 3673 0.2224 -0.1564
Hs 578T Afatinib
1.11
uM
LJP6
 72
hr
 658 3341 3761 0.8883 0.9080
MDA-MB-231 Alpelisib
3.33
uM
LJP5
 72
hr
 1235 4249 4660 0.9106 0.9034
BT-20 Alpelisib
3.33
uM
LJP5
 72
hr
 1097 1241 3846 0.3224 0.0683
SK-BR-3 Alpelisib
10
uM
LJP5
 72
hr
 1401 1593 4245 0.3756 0.0817