LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 A443654
3.33
uM
LJP6
 72
hr
 1209 636 4012 0.1589 -0.3108
MDA-MB-231 A443654
1.11
uM
LJP6
 72
hr
 1235 525 4405 0.1199 -0.3748
MCF7 A443654
1.11
uM
LJP6
 72
hr
 1209 631 4012 0.1570 -0.3152
MCF7 A443654
0.12
uM
LJP6
 72
hr
 1209 874 4012 0.2179 -0.1724
MDA-MB-231 A443654
10
uM
LJP6
 72
hr
 1235 344 4405 0.0782 -0.5024
SK-BR-3 A443654
0.12
uM
LJP6
 72
hr
 1401 1287 4168 0.3092 -0.0525
MCF7 A443654
0.37
uM
LJP6
 72
hr
 1209 491 4012 0.1226 -0.4072
MDA-MB-231 A443654
3.33
uM
LJP6
 72
hr
 1235 414 4405 0.0940 -0.4497
MCF7 A443654
0.04
uM
LJP6
 72
hr
 1209 1361 4012 0.3394 0.0696
Hs 578T A443654
1.11
uM
LJP6
 72
hr
 658 308 3761 0.0819 -0.2618
Hs 578T A443654
3.33
uM
LJP6
 72
hr
 658 294 3761 0.0781 -0.2747
MDA-MB-231 Afatinib
1.11
uM
LJP6
 72
hr
 1235 2739 4405 0.6225 0.5442
BT-20 Afatinib
1.11
uM
LJP6
 72
hr
 1097 3152 3673 0.8581 0.8317
MDA-MB-231 Afatinib
3.33
uM
LJP6
 72
hr
 1235 2749 4405 0.6241 0.5463
MDA-MB-231 Afatinib
10
uM
LJP6
 72
hr
 1235 628 4405 0.1427 -0.3090
BT-20 Afatinib
3.33
uM
LJP6
 72
hr
 1097 3253 3673 0.8856 0.8654
MDA-MB-231 Afatinib
0.04
uM
LJP6
 72
hr
 1235 4254 4405 0.9654 0.9608
BT-20 Afatinib
0.12
uM
LJP6
 72
hr
 1097 3032 3673 0.8258 0.7919
BT-20 Afatinib
0.37
uM
LJP6
 72
hr
 1097 3081 3673 0.8390 0.8076
BT-20 Afatinib
10
uM
LJP6
 72
hr
 1097 816 3673 0.2224 -0.1564
SK-BR-3 Afatinib
3.33
uM
LJP6
 72
hr
 1401 1550 4168 0.3716 0.0641
MCF7 Afatinib
10
uM
LJP6
 72
hr
 1209 922 4012 0.2304 -0.1451
SK-BR-3 Afatinib
10
uM
LJP6
 72
hr
 1401 1223 4168 0.2935 -0.0830
MCF7 Afatinib
0.04
uM
LJP6
 72
hr
 1209 3665 4012 0.9147 0.9003
MCF7 Afatinib
0.12
uM
LJP6
 72
hr
 1209 3666 4012 0.9160 0.9019