LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T AZD-6482
10
uM
LJP5
 72
hr
 658 1861 3933 0.4732 0.4960
Hs 578T AZD-6482
3.33
uM
LJP5
 72
hr
 658 2928 3933 0.7444 0.7831
Hs 578T AZD7762
0.04
uM
LJP6
 72
hr
 658 2131 3761 0.5665 0.5953
MCF7 AZD7762
0.37
uM
LJP6
 72
hr
 1209 1453 4012 0.3622 0.1113
MCF7 AZD7762
0.12
uM
LJP6
 72
hr
 1209 1692 4012 0.4224 0.2147
MDA-MB-231 AZD7762
0.12
uM
LJP6
 72
hr
 1235 2007 4405 0.4560 0.3028
Hs 578T AZD7762
0.12
uM
LJP6
 72
hr
 658 968 3761 0.2572 0.1635
SK-BR-3 AZD7762
0.04
uM
LJP6
 72
hr
 1401 1907 4168 0.4574 0.2158
SK-BR-3 AZD7762
0.37
uM
LJP6
 72
hr
 1401 1341 4168 0.3216 -0.0285
MCF7 AZD7762
0.04
uM
LJP6
 72
hr
 1209 1961 4012 0.4890 0.3221
Hs 578T AZD7762
0.37
uM
LJP6
 72
hr
 658 632 3761 0.1681 -0.0170
MDA-MB-231 AZD7762
0.37
uM
LJP6
 72
hr
 1235 1162 4405 0.2631 -0.0361
SK-BR-3 AZD7762
0.12
uM
LJP6
 72
hr
 1401 1526 4168 0.3660 0.0552
MCF7 AZD7762
3.33
uM
LJP6
 72
hr
 1209 993 4012 0.2477 -0.1080
BT-20 AZD7762
0.04
uM
LJP6
 72
hr
 1097 3676 3673 1.0006 1.0000
MCF7 AZD7762
10
uM
LJP6
 72
hr
 1209 617 4012 0.1545 -0.3225
MDA-MB-231 AZD7762
3.33
uM
LJP6
 72
hr
 1235 497 4405 0.1131 -0.3916
MDA-MB-231 AZD7762
1.11
uM
LJP6
 72
hr
 1235 729 4405 0.1653 -0.2512
SK-BR-3 AZD7762
1.11
uM
LJP6
 72
hr
 1401 1112 4168 0.2665 -0.1380
BT-20 AZD7762
3.33
uM
LJP6
 72
hr
 1097 750 3673 0.2042 -0.1962
MCF 10A AZD7762
3.33
uM
LJP6
 72
hr
 962 1659 10692 0.1552 0.1693
BT-20 AZD7762
0.37
uM
LJP6
 72
hr
 1097 2115 3673 0.5756 0.4564
MDA-MB-231 AZD7762
0.04
uM
LJP6
 72
hr
 1235 3180 4405 0.7227 0.6749
MDA-MB-231 AZD7762
10
uM
LJP6
 72
hr
 1235 409 4405 0.0926 -0.4545
BT-20 AZD7762
0.12
uM
LJP6
 72
hr
 1097 2846 3673 0.7742 0.7255