LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 Mitoxantrone
3.33
uM
LJP5
 72
hr
 1097 691 3846 0.1798 -0.2262
BT-20 Mitoxantrone
3.33
uM
LJP6
 72
hr
 1097 657 3673 0.1793 -0.2551
SK-BR-3 WZ3105
3.33
uM
LJP5
 72
hr
 1401 957 4245 0.2251 -0.2150
MCF7 HG-5-113-01
3.33
uM
LJP5
 72
hr
 1209 1316 4203 0.3136 0.0480
MCF 10A XMD11-50
3.33
uM
LJP6
 72
hr
 962 2653 10692 0.2481 0.3390
BT-20 Seliciclib
3.33
uM
LJP5
 72
hr
 1097 2834 3846 0.7370 0.6889
BT-20 Radicicol
3.33
uM
LJP5
 72
hr
 1097 968 3846 0.2518 -0.0669
BT-20 Radicicol
3.33
uM
LJP6
 72
hr
 1097 1007 3673 0.2743 -0.0480
SK-BR-3 Seliciclib
3.33
uM
LJP5
 72
hr
 1401 3235 4245 0.7609 0.6836
MDA-MB-231 BI-2536
3.33
uM
LJP6
 72
hr
 1235 1091 4405 0.2472 -0.0684
MCF 10A R406
3.33
uM
LJP6
 72
hr
 962 7814 10692 0.7310 0.8266
MCF7 XMD11-50
3.33
uM
LJP6
 72
hr
 1209 1687 4012 0.4209 0.2123
MDA-MB-231 Withaferin A
3.33
uM
LJP6
 72
hr
 1235 898 4405 0.2049 -0.1630
BT-20 Withaferin A
3.33
uM
LJP5
 72
hr
 1097 568 3846 0.1480 -0.3047
BT-20 Withaferin A
3.33
uM
LJP6
 72
hr
 1097 535 3673 0.1458 -0.3376