LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Tozasertib
3.33
uM
LJP5
 72
hr
 1209 1426 4203 0.3400 0.0963
MCF7 Seliciclib
0.37
uM
LJP5
 72
hr
 1209 3931 4203 0.9357 0.9273
MCF7 CGP60474
0.04
uM
LJP5
 72
hr
 1209 3388 4203 0.8081 0.7768
MCF7 CGP60474
0.37
uM
LJP5
 72
hr
 1209 566 4203 0.1350 -0.3455
MCF7 CP466722
0.04
uM
LJP5
 72
hr
 1209 4412 4203 1.0522 1.0586
MCF7 CP466722
0.12
uM
LJP5
 72
hr
 1209 4175 4203 0.9932 0.9920
MCF7 CP466722
0.37
uM
LJP5
 72
hr
 1209 4156 4203 0.9898 0.9893
MCF7 CP466722
1.11
uM
LJP5
 72
hr
 1209 3824 4203 0.9113 0.8991
MCF7 CP466722
3.33
uM
LJP5
 72
hr
 1209 3332 4203 0.7963 0.7620
MCF7 CP466722
10
uM
LJP5
 72
hr
 1209 1742 4203 0.4146 0.2244
MCF7 CP724714
0.04
uM
LJP5
 72
hr
 1209 3813 4203 0.9088 0.8972
MCF7 CP724714
0.12
uM
LJP5
 72
hr
 1209 3746 4203 0.8906 0.8736
MCF7 CP724714
0.37
uM
LJP5
 72
hr
 1209 3529 4203 0.8399 0.8145
MCF7 CP724714
1.11
uM
LJP5
 72
hr
 1209 3699 4203 0.8820 0.8656
MCF7 CP724714
3.33
uM
LJP5
 72
hr
 1209 3762 4203 0.8966 0.8829
MCF7 CP724714
10
uM
LJP5
 72
hr
 1209 2778 4203 0.6601 0.5857
MCF7 HG-5-113-01
10
uM
LJP5
 72
hr
 1209 569 4203 0.1358 -0.3430
MCF7 Neratinib
0.37
uM
LJP5
 72
hr
 1209 2753 4203 0.6563 0.5821
MCF7 Neratinib
1.11
uM
LJP5
 72
hr
 1209 1594 4203 0.3800 0.1664
MCF7 Neratinib
10
uM
LJP5
 72
hr
 1209 1377 4203 0.3283 0.0751
MCF7 Dasatinib
0.04
uM
LJP5
 72
hr
 1209 3206 4203 0.7621 0.7182
MCF7 Seliciclib
10
uM
LJP5
 72
hr
 1209 1223 4203 0.2908 0.0047
MCF7 Dasatinib
10
uM
LJP5
 72
hr
 1209 1660 4203 0.3954 0.1920
MCF7 Crizotinib
0.12
uM
LJP5
 72
hr
 1209 3523 4203 0.8394 0.8147
MCF7 Crizotinib
0.04
uM
LJP5
 72
hr
 1209 3621 4203 0.8617 0.8409