LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PF477736 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1146 | 4245 | 0.2708 | -0.1186 |
| SK-BR-3 | PF477736 | 10 | uM | LJP5 | 72 | hr | 1401 | 1190 | 4245 | 0.2803 | -0.0998 |
| SK-BR-3 | LDN-193189 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4952 | 4245 | 1.1690 | 1.2085 |
| SK-BR-3 | LDN-193189 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4081 | 4245 | 0.9574 | 0.9402 |
| SK-BR-3 | LDN-193189 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4428 | 4245 | 1.0447 | 1.0569 |
| SK-BR-3 | LDN-193189 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4146 | 4245 | 0.9745 | 0.9650 |
| SK-BR-3 | LDN-193189 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1026 | 4245 | 0.2352 | -0.2188 |
| SK-BR-3 | LDN-193189 | 10 | uM | LJP5 | 72 | hr | 1401 | 557 | 4245 | 0.1286 | -0.4568 |
| SK-BR-3 | PF431396 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4406 | 4245 | 1.0430 | 1.0574 |
| SK-BR-3 | PF431396 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 3284 | 4245 | 0.7780 | 0.7108 |
| SK-BR-3 | PF431396 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 2164 | 4245 | 0.5112 | 0.3136 |
| SK-BR-3 | PF431396 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1659 | 4245 | 0.3932 | 0.1128 |
| SK-BR-3 | PF431396 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1521 | 4245 | 0.3617 | 0.0551 |
| SK-BR-3 | PF431396 | 10 | uM | LJP5 | 72 | hr | 1401 | 1345 | 4245 | 0.3189 | -0.0245 |
| SK-BR-3 | Celastrol | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3226 | 4168 | 0.7743 | 0.6998 |
| SK-BR-3 | Celastrol | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3535 | 4168 | 0.8487 | 0.8001 |
| SK-BR-3 | Celastrol | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1875 | 4168 | 0.4495 | 0.2011 |
| SK-BR-3 | Celastrol | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1280 | 4168 | 0.3068 | -0.0574 |
| SK-BR-3 | Celastrol | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1162 | 4168 | 0.2790 | -0.1123 |
| SK-BR-3 | Celastrol | 10 | uM | LJP6 | 72 | hr | 1401 | 1126 | 4168 | 0.2703 | -0.1301 |
| SK-BR-3 | SU11274 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4495 | 4245 | 1.0566 | 1.0667 |
| SK-BR-3 | SU11274 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4255 | 4245 | 1.0006 | 0.9986 |
| SK-BR-3 | SU11274 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4486 | 4245 | 1.0566 | 1.0702 |
| SK-BR-3 | SU11274 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4034 | 4245 | 0.9491 | 0.9341 |
| SK-BR-3 | SU11274 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 3915 | 4245 | 0.9204 | 0.8961 |