LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 CP724714
1.11
uM
LJP5
 72
hr
 1097 3148 3846 0.8192 0.7904
BT-20 CP724714
10
uM
LJP5
 72
hr
 1097 2233 3846 0.5792 0.4746
BT-20 Alvocidib
0.04
uM
LJP6
 72
hr
 1097 1075 3673 0.2930 -0.0116
BT-20 Alvocidib
3.33
uM
LJP6
 72
hr
 1097 635 3673 0.1731 -0.2694
BT-20 Alvocidib
10
uM
LJP6
 72
hr
 1097 586 3673 0.1596 -0.3025
BT-20 GW843682X
0.12
uM
LJP6
 72
hr
 1097 2174 3673 0.5918 0.4792
BT-20 GW843682X
0.37
uM
LJP6
 72
hr
 1097 1471 3673 0.4008 0.1835
BT-20 GW843682X
10
uM
LJP6
 72
hr
 1097 1622 3673 0.4425 0.2500
BT-20 HG-5-113-01
0.04
uM
LJP5
 72
hr
 1097 3850 3846 1.0008 1.0003
BT-20 HG-5-113-01
0.37
uM
LJP5
 72
hr
 1097 3391 3846 0.8812 0.8641
BT-20 HG-5-113-01
1.11
uM
LJP5
 72
hr
 1097 2722 3846 0.7077 0.6515
BT-20 HG-5-88-01
1.11
uM
LJP6
 72
hr
 1097 3264 3673 0.8885 0.8687
BT-20 HG-5-88-01
3.33
uM
LJP6
 72
hr
 1097 3320 3673 0.9036 0.8866
BT-20 HG-6-64-01
0.04
uM
LJP6
 72
hr
 1097 3336 3673 0.9080 0.8919
BT-20 HG-6-64-01
0.12
uM
LJP6
 72
hr
 1097 2796 3673 0.7610 0.7098
BT-20 HG-6-64-01
3.33
uM
LJP6
 72
hr
 1097 1560 3673 0.4252 0.2241
BT-20 HG-6-64-01
10
uM
LJP6
 72
hr
 1097 627 3673 0.1708 -0.2747
BT-20 Neratinib
0.12
uM
LJP5
 72
hr
 1097 2626 3846 0.6824 0.6184
BT-20 Neratinib
0.37
uM
LJP5
 72
hr
 1097 2260 3846 0.5873 0.4890
BT-20 JW-7-24-1
0.04
uM
LJP6
 72
hr
 1097 2963 3673 0.8073 0.7687
BT-20 JW-7-24-1
0.12
uM
LJP6
 72
hr
 1097 3059 3673 0.8331 0.8010
BT-20 JW-7-24-1
1.11
uM
LJP6
 72
hr
 1097 2370 3673 0.6458 0.5549
BT-20 JW-7-24-1
3.33
uM
LJP6
 72
hr
 1097 1812 3673 0.4932 0.3327
BT-20 PF562271
10
uM
LJP6
 72
hr
 1097 700 3673 0.1909 -0.2270
BT-20 PF562271
3.33
uM
LJP6
 72
hr
 1097 1359 3673 0.3699 0.1300