LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A HG-6-64-01
0.04
uM
LJP6
 72
hr
 962 10078 10692 0.9425 0.9661
MCF 10A Alvocidib
0.04
uM
LJP6
 72
hr
 962 722 10692 0.0676 -0.0804
MCF 10A Alvocidib
3.33
uM
LJP6
 72
hr
 962 204 10692 0.0191 -0.3608
MCF 10A Alvocidib
0.12
uM
LJP6
 72
hr
 962 320 10692 0.0299 -0.2716
MCF 10A Alvocidib
0.37
uM
LJP6
 72
hr
 962 200 10692 0.0187 -0.3636
MCF 10A AT-7519
0.04
uM
LJP6
 72
hr
 962 9592 10692 0.8971 0.9382
MCF 10A AZD7762
0.37
uM
LJP6
 72
hr
 962 6489 10692 0.6069 0.7322
MCF 10A GW843682X
0.12
uM
LJP6
 72
hr
 962 6712 10692 0.6278 0.7491
MCF 10A GW843682X
0.37
uM
LJP6
 72
hr
 962 2477 10692 0.2318 0.3123
MCF 10A AT-7519
0.12
uM
LJP6
 72
hr
 962 7625 10692 0.7132 0.8145
MCF 10A AT-7519
0.37
uM
LJP6
 72
hr
 962 595 10692 0.0557 -0.1298
MCF 10A AT-7519
3.33
uM
LJP6
 72
hr
 962 194 10692 0.0181 -0.3695
MCF 10A AT-7519
10
uM
LJP6
 72
hr
 962 195 10692 0.0183 -0.3686
MCF 10A AZD7762
1.11
uM
LJP6
 72
hr
 962 3756 10692 0.3513 0.4793
MCF 10A AZD7762
3.33
uM
LJP6
 72
hr
 962 1659 10692 0.1552 0.1693
MCF 10A AZD8055
0.04
uM
LJP6
 72
hr
 962 3374 10692 0.3157 0.4335
MCF 10A AZD8055
0.12
uM
LJP6
 72
hr
 962 2256 10692 0.2111 0.2779
MCF 10A AZD8055
3.33
uM
LJP6
 72
hr
 962 1501 10692 0.1404 0.1361
MCF 10A AZD8055
10
uM
LJP6
 72
hr
 962 57 10692 0.0053 -0.5572
MCF 10A Sorafenib
0.12
uM
LJP6
 72
hr
 962 9665 10692 0.9041 0.9423
MCF 10A Sorafenib
0.37
uM
LJP6
 72
hr
 962 9369 10692 0.8764 0.9253
MCF 10A Alvocidib
10
uM
LJP6
 72
hr
 962 252 10692 0.0236 -0.3198
MCF 10A HG-5-88-01
0.12
uM
LJP6
 72
hr
 962 9724 10692 0.9095 0.9461
MCF 10A JW-7-24-1
0.12
uM
LJP6
 72
hr
 962 10510 10692 0.9830 0.9902
MCF 10A JW-7-24-1
0.04
uM
LJP6
 72
hr
 962 10930 10692 1.0224 1.0127