LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Alvocidib
1.11
uM
LJP6
72
hr
962 212 10692 0.0198 -0.3536
MCF 10A Canertinib
10
uM
LJP6
72
hr
962 208 10692 0.0195 -0.3567
MCF 10A Alvocidib
3.33
uM
LJP6
72
hr
962 204 10692 0.0191 -0.3608
MCF 10A Alvocidib
0.37
uM
LJP6
72
hr
962 200 10692 0.0187 -0.3636
MDA-MB-231 Mitoxantrone
10
uM
LJP5
72
hr
1235 86 4660 0.0186 -0.7515
MCF 10A AT-7519
10
uM
LJP6
72
hr
962 195 10692 0.0183 -0.3686
MCF 10A AT-7519
3.33
uM
LJP6
72
hr
962 194 10692 0.0181 -0.3695
MCF 10A WZ3105
10
uM
LJP5
72
hr
962 185 10512 0.0176 -0.3840
MCF7 Mitoxantrone
10
uM
LJP6
72
hr
1209 70 4012 0.0175 -0.8076
MCF 10A A443654
10
uM
LJP6
72
hr
962 173 10692 0.0162 -0.3911
Hs 578T PHA-665752
10
uM
LJP5
72
hr
658 53 3933 0.0136 -0.6240
MCF 10A LDN-193189
10
uM
LJP5
72
hr
962 136 10512 0.0130 -0.4374
Hs 578T Mitoxantrone
10
uM
LJP6
72
hr
658 35 3761 0.0093 -0.6912
Hs 578T Mitoxantrone
10
uM
LJP5
72
hr
658 25 3933 0.0064 -0.7202
MCF 10A AZD8055
10
uM
LJP6
72
hr
962 57 10692 0.0053 -0.5572