LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Luminespib | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1582 | 4245 | 0.3723 | 0.0750 |
| SK-BR-3 | Luminespib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1599 | 4245 | 0.3763 | 0.0830 |
| SK-BR-3 | Luminespib | 10 | uM | LJP5 | 72 | hr | 1401 | 1571 | 4245 | 0.3705 | 0.0732 |
| SK-BR-3 | AZD8330 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 3062 | 4245 | 0.7205 | 0.6272 |
| SK-BR-3 | AZD8330 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 3257 | 4245 | 0.7662 | 0.6911 |
| SK-BR-3 | AZD8330 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 3474 | 4245 | 0.8204 | 0.7681 |
| SK-BR-3 | AZD8330 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 3696 | 4245 | 0.8707 | 0.8335 |
| SK-BR-3 | AZD8330 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 3680 | 4245 | 0.8688 | 0.8324 |
| SK-BR-3 | AZD8330 | 10 | uM | LJP5 | 72 | hr | 1401 | 3926 | 4245 | 0.9241 | 0.9025 |
| SK-BR-3 | TGX221 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 3463 | 4245 | 0.8163 | 0.7607 |
| SK-BR-3 | TGX221 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 3744 | 4245 | 0.8793 | 0.8415 |
| SK-BR-3 | TGX221 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4060 | 4245 | 0.9556 | 0.9430 |
| SK-BR-3 | TGX221 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4142 | 4245 | 0.9742 | 0.9658 |
| SK-BR-3 | TGX221 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 4210 | 4245 | 0.9911 | 0.9882 |
| SK-BR-3 | TGX221 | 10 | uM | LJP5 | 72 | hr | 1401 | 3799 | 4245 | 0.8966 | 0.8692 |
| SK-BR-3 | GSK1059615 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4469 | 4245 | 1.0545 | 1.0696 |
| SK-BR-3 | GSK1059615 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3841 | 4168 | 0.9233 | 0.9002 |
| SK-BR-3 | GSK1059615 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 3743 | 4245 | 0.8803 | 0.8409 |
| SK-BR-3 | GSK1059615 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3420 | 4168 | 0.8211 | 0.7645 |
| SK-BR-3 | GSK1059615 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 2987 | 4245 | 0.7038 | 0.6045 |
| SK-BR-3 | GSK1059615 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3031 | 4168 | 0.7275 | 0.6337 |
| SK-BR-3 | GSK1059615 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1742 | 4245 | 0.4090 | 0.1396 |
| SK-BR-3 | GSK1059615 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1675 | 4168 | 0.4018 | 0.1198 |
| SK-BR-3 | GSK1059615 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 995 | 4245 | 0.2310 | -0.2155 |
| SK-BR-3 | GSK1059615 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 956 | 4168 | 0.2297 | -0.2170 |