LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Nintedanib | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3918 | 4168 | 0.9406 | 0.9237 |
| SK-BR-3 | Nintedanib | 1.11 | uM | LJP6 | 72 | hr | 1401 | 3638 | 4168 | 0.8722 | 0.8325 |
| SK-BR-3 | Nintedanib | 3.33 | uM | LJP6 | 72 | hr | 1401 | 3279 | 4168 | 0.7872 | 0.7179 |
| SK-BR-3 | Nintedanib | 10 | uM | LJP6 | 72 | hr | 1401 | 1350 | 4168 | 0.3238 | -0.0249 |
| SK-BR-3 | Foretinib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4620 | 4245 | 1.0893 | 1.1112 |
| SK-BR-3 | Foretinib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4409 | 4245 | 1.0374 | 1.0454 |
| SK-BR-3 | Foretinib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1773 | 4245 | 0.4173 | 0.1554 |
| SK-BR-3 | Foretinib | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1448 | 4245 | 0.3417 | 0.0199 |
| SK-BR-3 | Foretinib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1485 | 4245 | 0.3500 | 0.0351 |
| SK-BR-3 | Foretinib | 10 | uM | LJP5 | 72 | hr | 1401 | 1352 | 4245 | 0.3194 | -0.0225 |
| SK-BR-3 | AZD 5438 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3734 | 4168 | 0.8954 | 0.8635 |
| SK-BR-3 | AZD 5438 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3016 | 4168 | 0.7237 | 0.6277 |
| SK-BR-3 | AZD 5438 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 2355 | 4168 | 0.5646 | 0.3898 |
| SK-BR-3 | AZD 5438 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1208 | 4168 | 0.2897 | -0.0907 |
| SK-BR-3 | AZD 5438 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1046 | 4168 | 0.2510 | -0.1703 |
| SK-BR-3 | AZD 5438 | 10 | uM | LJP6 | 72 | hr | 1401 | 793 | 4168 | 0.1902 | -0.3041 |
| SK-BR-3 | Pelitinib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 2346 | 4245 | 0.5526 | 0.3778 |
| SK-BR-3 | Pelitinib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 1671 | 4245 | 0.3936 | 0.1143 |
| SK-BR-3 | Pelitinib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1455 | 4245 | 0.3433 | 0.0219 |
| SK-BR-3 | Pelitinib | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1389 | 4245 | 0.3287 | -0.0047 |
| SK-BR-3 | Pelitinib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1398 | 4245 | 0.3314 | -0.0018 |
| SK-BR-3 | Pelitinib | 10 | uM | LJP5 | 72 | hr | 1401 | 1087 | 4245 | 0.2581 | -0.1465 |
| SK-BR-3 | Luminespib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 1644 | 4245 | 0.3868 | 0.1014 |
| SK-BR-3 | Luminespib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 1580 | 4245 | 0.3722 | 0.0759 |
| SK-BR-3 | Luminespib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1584 | 4245 | 0.3716 | 0.0733 |