LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | GDC-0980 | 0.37 | uM | LJP5 | 72 | hr | 1209 | 1023 | 4203 | 0.2440 | -0.0887 |
| MCF7 | GDC-0980 | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1026 | 4203 | 0.2450 | -0.0872 |
| MCF7 | GDC-0980 | 3.33 | uM | LJP5 | 72 | hr | 1209 | 1004 | 4203 | 0.2391 | -0.0989 |
| MCF7 | GDC-0980 | 10 | uM | LJP5 | 72 | hr | 1209 | 1083 | 4203 | 0.2578 | -0.0602 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP5 | 72 | hr | 1209 | 1239 | 4203 | 0.2951 | 0.0132 |
| MCF7 | Mitoxantrone | 0.04 | uM | LJP6 | 72 | hr | 1209 | 1258 | 4012 | 0.3139 | 0.0229 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP5 | 72 | hr | 1209 | 1270 | 4203 | 0.3031 | 0.0282 |
| MCF7 | Mitoxantrone | 0.12 | uM | LJP6 | 72 | hr | 1209 | 1236 | 4012 | 0.3091 | 0.0133 |
| MCF7 | Mitoxantrone | 0.37 | uM | LJP5 | 72 | hr | 1209 | 1193 | 4203 | 0.2841 | -0.0081 |
| MCF7 | Mitoxantrone | 0.37 | uM | LJP6 | 72 | hr | 1209 | 1233 | 4012 | 0.3079 | 0.0115 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 1209 | 691 | 4203 | 0.1645 | -0.2684 |
| MCF7 | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 1209 | 694 | 4012 | 0.1729 | -0.2756 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP5 | 72 | hr | 1209 | 530 | 4203 | 0.1262 | -0.3687 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP6 | 72 | hr | 1209 | 499 | 4012 | 0.1242 | -0.4019 |
| MCF7 | Mitoxantrone | 10 | uM | LJP5 | 72 | hr | 1209 | 89 | 4203 | 0.0213 | -0.7655 |
| MCF7 | Mitoxantrone | 10 | uM | LJP6 | 72 | hr | 1209 | 70 | 4012 | 0.0175 | -0.8076 |
| MCF7 | Radicicol | 0.04 | uM | LJP5 | 72 | hr | 1209 | 2692 | 4203 | 0.6413 | 0.5618 |
| MCF7 | Radicicol | 0.04 | uM | LJP6 | 72 | hr | 1209 | 2453 | 4012 | 0.6121 | 0.5058 |
| MCF7 | Radicicol | 0.12 | uM | LJP5 | 72 | hr | 1209 | 1864 | 4203 | 0.4430 | 0.2698 |
| MCF7 | Radicicol | 0.12 | uM | LJP6 | 72 | hr | 1209 | 1778 | 4012 | 0.4437 | 0.2498 |
| MCF7 | Radicicol | 0.37 | uM | LJP5 | 72 | hr | 1209 | 1564 | 4203 | 0.3721 | 0.1528 |
| MCF7 | Radicicol | 0.37 | uM | LJP6 | 72 | hr | 1209 | 1432 | 4012 | 0.3575 | 0.1028 |
| MCF7 | Radicicol | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1393 | 4203 | 0.3321 | 0.0821 |
| MCF7 | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 1209 | 1436 | 4012 | 0.3584 | 0.1046 |
| MCF7 | Radicicol | 3.33 | uM | LJP5 | 72 | hr | 1209 | 1429 | 4203 | 0.3410 | 0.0971 |