LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | XL147 | 3.33 | uM | LJP5 | 72 | hr | 1209 | 4318 | 4203 | 1.0277 | 1.0308 |
| MCF7 | XL147 | 10 | uM | LJP5 | 72 | hr | 1209 | 3097 | 4203 | 0.7373 | 0.6877 |
| MCF7 | Y39983 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 4386 | 4012 | 1.0946 | 1.1082 |
| MCF7 | Y39983 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 4310 | 4012 | 1.0745 | 1.0854 |
| MCF7 | Y39983 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 4177 | 4012 | 1.0403 | 1.0453 |
| MCF7 | Y39983 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 4045 | 4012 | 1.0094 | 1.0118 |
| MCF7 | Y39983 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 3292 | 4012 | 0.8227 | 0.7870 |
| MCF7 | Y39983 | 10 | uM | LJP6 | 72 | hr | 1209 | 642 | 4012 | 0.1600 | -0.3072 |
| MCF7 | Nintedanib | 0.04 | uM | LJP6 | 72 | hr | 1209 | 4173 | 4012 | 1.0413 | 1.0482 |
| MCF7 | Nintedanib | 0.12 | uM | LJP6 | 72 | hr | 1209 | 3927 | 4012 | 0.9785 | 0.9748 |
| MCF7 | Nintedanib | 0.37 | uM | LJP6 | 72 | hr | 1209 | 3494 | 4012 | 0.8716 | 0.8476 |
| MCF7 | Nintedanib | 1.11 | uM | LJP6 | 72 | hr | 1209 | 2818 | 4012 | 0.7016 | 0.6282 |
| MCF7 | Nintedanib | 3.33 | uM | LJP6 | 72 | hr | 1209 | 2411 | 4012 | 0.6011 | 0.4897 |
| MCF7 | Nintedanib | 10 | uM | LJP6 | 72 | hr | 1209 | 1386 | 4012 | 0.3453 | 0.0808 |
| MCF7 | Foretinib | 0.04 | uM | LJP5 | 72 | hr | 1209 | 4323 | 4203 | 1.0304 | 1.0340 |
| MCF7 | Foretinib | 0.12 | uM | LJP5 | 72 | hr | 1209 | 2856 | 4203 | 0.6794 | 0.6120 |
| MCF7 | Foretinib | 0.37 | uM | LJP5 | 72 | hr | 1209 | 1490 | 4203 | 0.3548 | 0.1225 |
| MCF7 | Foretinib | 1.11 | uM | LJP5 | 72 | hr | 1209 | 1355 | 4203 | 0.3233 | 0.0660 |
| MCF7 | Foretinib | 3.33 | uM | LJP5 | 72 | hr | 1209 | 1209 | 4203 | 0.2874 | -0.0019 |
| MCF7 | Foretinib | 10 | uM | LJP5 | 72 | hr | 1209 | 745 | 4203 | 0.1780 | -0.2366 |
| MCF7 | AZD 5438 | 0.04 | uM | LJP6 | 72 | hr | 1209 | 2897 | 4012 | 0.7209 | 0.6534 |
| MCF7 | AZD 5438 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 1817 | 4012 | 0.4520 | 0.2615 |
| MCF7 | AZD 5438 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 1175 | 4012 | 0.2918 | -0.0214 |
| MCF7 | AZD 5438 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 768 | 4012 | 0.1908 | -0.2340 |
| MCF7 | AZD 5438 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 669 | 4012 | 0.1664 | -0.2923 |