LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | A443654 | 10 | uM | LJP6 | 72 | hr | 1311 | 454 | 4935 | 0.0922 | -0.4257 |
| BT-20 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1334 | 809 | 3925 | 0.2063 | -0.2747 |
| MDA-MB-231 | A443654 | 0.12 | uM | LJP6 | 72 | hr | 1311 | 3262 | 4935 | 0.6612 | 0.6106 |
| MDA-MB-231 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1311 | 1131 | 4935 | 0.2292 | -0.0750 |
| BT-20 | A443654 | 0.12 | uM | LJP6 | 72 | hr | 1334 | 2994 | 3925 | 0.7629 | 0.6805 |
| BT-20 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 1361 | 3925 | 0.3468 | 0.0126 |
| SK-BR-3 | A443654 | 10 | uM | LJP6 | 72 | hr | 2543 | 1031 | 5418 | 0.1903 | -0.5635 |
| MDA-MB-231 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 1311 | 3906 | 4935 | 0.7916 | 0.7697 |
| SK-BR-3 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1204 | 5418 | 0.2225 | -0.4962 |
| MDA-MB-231 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1311 | 1147 | 4935 | 0.2326 | -0.0682 |
| BT-20 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 1334 | 3139 | 3925 | 0.7998 | 0.7316 |
| SK-BR-3 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1182 | 5418 | 0.2179 | -0.5053 |
| BT-20 | A443654 | 0.37 | uM | LJP6 | 72 | hr | 1334 | 2004 | 3925 | 0.5108 | 0.2985 |
| MCF7 | A443654 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 803 | 5445 | 0.1477 | -0.2433 |
| MCF7 | A443654 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 1052 | 5445 | 0.1933 | -0.1323 |
| SK-BR-3 | A443654 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 1321 | 5418 | 0.2439 | -0.4518 |
| MCF7 | A443654 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 804 | 5445 | 0.1473 | -0.2445 |
| MCF7 | A443654 | 10 | uM | LJP6 | 72 | hr | 1389 | 547 | 5445 | 0.1004 | -0.3780 |
| MCF7 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 1389 | 1385 | 5445 | 0.2540 | -0.0037 |
| SK-BR-3 | A443654 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 1373 | 5418 | 0.2534 | -0.4322 |
| MDA-MB-231 | A443654 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 1805 | 4935 | 0.3659 | 0.1813 |
| SK-BR-3 | A443654 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 1613 | 5418 | 0.2978 | -0.3416 |
| MCF7 | A443654 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 886 | 5445 | 0.1622 | -0.2067 |
| Hs 578T | A443654 | 0.04 | uM | LJP6 | 72 | hr | 765 | 1997 | 3101 | 0.6437 | 0.6075 |
| BT-20 | A443654 | 10 | uM | LJP6 | 72 | hr | 1334 | 232 | 3925 | 0.0593 | -0.6746 |