LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Saracatinib
0.04
uM
LJP6
 72
hr
 1389 4594 5445 0.8439 0.8347
MCF7 Saracatinib
0.12
uM
LJP6
 72
hr
 1389 3378 5445 0.6191 0.5647
MCF7 Saracatinib
0.37
uM
LJP6
 72
hr
 1389 2345 5445 0.4306 0.3029
MCF7 Saracatinib
1.11
uM
LJP6
 72
hr
 1389 1811 5445 0.3327 0.1431
MCF7 Saracatinib
3.33
uM
LJP6
 72
hr
 1389 1515 5445 0.2788 0.0446
MCF7 Saracatinib
10
uM
LJP6
 72
hr
 1389 1667 5445 0.3071 0.0976
MCF7 Sigma A6730
0.04
uM
LJP5
 72
hr
 1389 4389 5905 0.7430 0.7344
MCF7 Sigma A6730
0.12
uM
LJP5
 72
hr
 1389 4612 5905 0.7806 0.7759
MCF7 Sigma A6730
0.37
uM
LJP5
 72
hr
 1389 4775 5905 0.8083 0.8058
MCF7 Sigma A6730
1.11
uM
LJP5
 72
hr
 1389 3453 5905 0.5848 0.5467
MCF7 Sigma A6730
3.33
uM
LJP5
 72
hr
 1389 3455 5905 0.5842 0.5446
MCF7 Sigma A6730
10
uM
LJP5
 72
hr
 1389 1919 5905 0.3236 0.1584
MCF7 WH-4-025
0.04
uM
LJP5
 72
hr
 1389 5576 5905 0.9435 0.9443
MCF7 WH-4-025
0.12
uM
LJP5
 72
hr
 1389 3951 5905 0.6680 0.6467
MCF7 WH-4-025
0.37
uM
LJP5
 72
hr
 1389 3583 5905 0.6047 0.5660
MCF7 WH-4-025
1.11
uM
LJP5
 72
hr
 1389 1603 5905 0.2716 0.0711
MCF7 WH-4-025
3.33
uM
LJP5
 72
hr
 1389 1662 5905 0.2815 0.0896
MCF7 WH-4-025
10
uM
LJP5
 72
hr
 1389 1328 5905 0.2254 -0.0211
MCF7 R406
0.04
uM
LJP6
 72
hr
 1389 4780 5445 0.8774 0.8706
MCF7 R406
0.12
uM
LJP6
 72
hr
 1389 5075 5445 0.9308 0.9273
MCF7 R406
0.37
uM
LJP6
 72
hr
 1389 5010 5445 0.9192 0.9153
MCF7 R406
1.11
uM
LJP6
 72
hr
 1389 4320 5445 0.7919 0.7742
MCF7 R406
3.33
uM
LJP6
 72
hr
 1389 4113 5445 0.7561 0.7355
MCF7 R406
10
uM
LJP6
 72
hr
 1389 2309 5445 0.4230 0.2906
MCF7 BI-2536
0.04
uM
LJP6
 72
hr
 1389 1537 5445 0.2817 0.0501