LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 KIN001-043
0.12
uM
LJP6
 72
hr
 1311 4255 4935 0.8620 0.8486
MDA-MB-231 KIN001-043
0.37
uM
LJP6
 72
hr
 1311 4143 4935 0.8395 0.8238
MDA-MB-231 KIN001-043
1.11
uM
LJP6
 72
hr
 1311 4238 4935 0.8586 0.8463
MDA-MB-231 KIN001-043
3.33
uM
LJP6
 72
hr
 1311 4481 4935 0.9081 0.9016
MDA-MB-231 KIN001-043
10
uM
LJP6
 72
hr
 1311 2101 4935 0.4259 0.2793
MDA-MB-231 Saracatinib
0.04
uM
LJP6
 72
hr
 1311 4283 4935 0.8682 0.8573
MDA-MB-231 Saracatinib
0.12
uM
LJP6
 72
hr
 1311 3312 4935 0.6710 0.6222
MDA-MB-231 Saracatinib
0.37
uM
LJP6
 72
hr
 1311 2910 4935 0.5897 0.5162
MDA-MB-231 Saracatinib
1.11
uM
LJP6
 72
hr
 1311 2524 4935 0.5112 0.4073
MDA-MB-231 Saracatinib
3.33
uM
LJP6
 72
hr
 1311 2384 4935 0.4831 0.3657
MDA-MB-231 Saracatinib
10
uM
LJP6
 72
hr
 1311 2008 4935 0.4070 0.2489
MDA-MB-231 Sigma A6730
0.04
uM
LJP5
 72
hr
 1311 4443 5079 0.8750 0.8671
MDA-MB-231 Sigma A6730
0.12
uM
LJP5
 72
hr
 1311 4674 5079 0.9200 0.9162
MDA-MB-231 Sigma A6730
0.37
uM
LJP5
 72
hr
 1311 4755 5079 0.9359 0.9331
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 72
hr
 1311 4347 5079 0.8558 0.8464
MDA-MB-231 Sigma A6730
3.33
uM
LJP5
 72
hr
 1311 4571 5079 0.8997 0.8942
MDA-MB-231 Sigma A6730
10
uM
LJP5
 72
hr
 1311 3636 5079 0.7156 0.6846
MDA-MB-231 WH-4-025
0.04
uM
LJP5
 72
hr
 1311 4389 5079 0.8644 0.8551
MDA-MB-231 WH-4-025
0.12
uM
LJP5
 72
hr
 1311 3246 5079 0.6392 0.5886
MDA-MB-231 WH-4-025
0.37
uM
LJP5
 72
hr
 1311 2774 5079 0.5461 0.4670
MDA-MB-231 WH-4-025
1.11
uM
LJP5
 72
hr
 1311 1587 5079 0.3125 0.1010
MDA-MB-231 WH-4-025
3.33
uM
LJP5
 72
hr
 1311 1492 5079 0.2937 0.0677
MDA-MB-231 WH-4-025
10
uM
LJP5
 72
hr
 1311 1043 5079 0.2053 -0.1108
MDA-MB-231 R406
0.04
uM
LJP6
 72
hr
 1311 4938 4935 1.0004 0.9994
MDA-MB-231 R406
0.12
uM
LJP6
 72
hr
 1311 4919 4935 0.9970 0.9964