LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Tozasertib | 3.33 | uM | LJP5 | 72 | hr | 1389 | 1530 | 5905 | 0.2591 | 0.0471 |
| MCF7 | Tozasertib | 10 | uM | LJP5 | 72 | hr | 1389 | 1536 | 5905 | 0.2600 | 0.0487 |
| MCF7 | Imatinib | 0.04 | uM | LJP6 | 72 | hr | 1389 | 5983 | 5445 | 1.1007 | 1.1009 |
| MCF7 | Imatinib | 0.12 | uM | LJP6 | 72 | hr | 1389 | 6237 | 5445 | 1.1474 | 1.1453 |
| MCF7 | Imatinib | 0.37 | uM | LJP6 | 72 | hr | 1389 | 5801 | 5445 | 1.0656 | 1.0653 |
| MCF7 | Imatinib | 1.11 | uM | LJP6 | 72 | hr | 1389 | 5907 | 5445 | 1.0867 | 1.0872 |
| MCF7 | Imatinib | 3.33 | uM | LJP6 | 72 | hr | 1389 | 5850 | 5445 | 1.0778 | 1.0789 |
| MCF7 | Imatinib | 10 | uM | LJP6 | 72 | hr | 1389 | 4976 | 5445 | 0.9157 | 0.9133 |
| MCF7 | NVP-TAE684 | 0.04 | uM | LJP6 | 72 | hr | 1389 | 4311 | 5445 | 0.7910 | 0.7744 |
| MCF7 | NVP-TAE684 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 2262 | 5445 | 0.4158 | 0.2801 |
| MCF7 | NVP-TAE684 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 1715 | 5445 | 0.3148 | 0.1114 |
| MCF7 | NVP-TAE684 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1198 | 5445 | 0.2205 | -0.0725 |
| MCF7 | NVP-TAE684 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 1013 | 5445 | 0.1866 | -0.1481 |
| MCF7 | NVP-TAE684 | 10 | uM | LJP6 | 72 | hr | 1389 | 966 | 5445 | 0.1776 | -0.1687 |
| MCF7 | CGP60474 | 0.04 | uM | LJP5 | 72 | hr | 1389 | 5969 | 5905 | 1.0110 | 1.0106 |
| MCF7 | CGP60474 | 0.04 | uM | LJP6 | 72 | hr | 1389 | 727 | 5445 | 0.1339 | -0.2802 |
| MCF7 | CGP60474 | 0.12 | uM | LJP5 | 72 | hr | 1389 | 1029 | 5905 | 0.1735 | -0.1408 |
| MCF7 | CGP60474 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 659 | 5445 | 0.1217 | -0.3150 |
| MCF7 | CGP60474 | 0.37 | uM | LJP5 | 72 | hr | 1389 | 465 | 5905 | 0.0787 | -0.4081 |
| MCF7 | CGP60474 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 618 | 5445 | 0.1142 | -0.3372 |
| MCF7 | CGP60474 | 1.11 | uM | LJP5 | 72 | hr | 1389 | 397 | 5905 | 0.0672 | -0.4513 |
| MCF7 | CGP60474 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 581 | 5445 | 0.1067 | -0.3618 |
| MCF7 | CGP60474 | 3.33 | uM | LJP5 | 72 | hr | 1389 | 359 | 5905 | 0.0608 | -0.4776 |
| MCF7 | CGP60474 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 434 | 5445 | 0.0800 | -0.4480 |
| MCF7 | CGP60474 | 10 | uM | LJP5 | 72 | hr | 1389 | 343 | 5905 | 0.0581 | -0.4884 |