LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Enzastaurin | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5864 | 5752 | 1.0195 | 1.0331 |
| SK-BR-3 | Enzastaurin | 3.33 | uM | LJP5 | 72 | hr | 2543 | 5783 | 5752 | 1.0053 | 1.0088 |
| SK-BR-3 | Enzastaurin | 10 | uM | LJP5 | 72 | hr | 2543 | 6171 | 5752 | 1.0728 | 1.1228 |
| SK-BR-3 | Palbociclib | 0.04 | uM | LJP6 | 72 | hr | 2543 | 4893 | 5418 | 0.9038 | 0.8242 |
| SK-BR-3 | Palbociclib | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4466 | 5418 | 0.8249 | 0.6775 |
| SK-BR-3 | Palbociclib | 0.37 | uM | LJP6 | 72 | hr | 2543 | 4243 | 5418 | 0.7840 | 0.6013 |
| SK-BR-3 | Palbociclib | 1.11 | uM | LJP6 | 72 | hr | 2543 | 4116 | 5418 | 0.7605 | 0.5570 |
| SK-BR-3 | Palbociclib | 3.33 | uM | LJP6 | 72 | hr | 2543 | 4033 | 5418 | 0.7456 | 0.5295 |
| SK-BR-3 | Palbociclib | 10 | uM | LJP6 | 72 | hr | 2543 | 3847 | 5418 | 0.7111 | 0.4643 |
| SK-BR-3 | PF562271 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 5675 | 5418 | 1.0480 | 1.0891 |
| SK-BR-3 | PF562271 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 5530 | 5418 | 1.0215 | 1.0412 |
| SK-BR-3 | PF562271 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 4812 | 5418 | 0.8897 | 0.7996 |
| SK-BR-3 | PF562271 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 3045 | 5418 | 0.5628 | 0.1809 |
| SK-BR-3 | PF562271 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 2136 | 5418 | 0.3947 | -0.1475 |
| SK-BR-3 | PF562271 | 10 | uM | LJP6 | 72 | hr | 2543 | 1079 | 5418 | 0.1994 | -0.5446 |
| SK-BR-3 | PHA-793887 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 2708 | 5418 | 0.4999 | 0.0588 |
| SK-BR-3 | PHA-793887 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 2647 | 5418 | 0.4891 | 0.0381 |
| SK-BR-3 | PHA-793887 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 2348 | 5418 | 0.4341 | -0.0697 |
| SK-BR-3 | PHA-793887 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 2231 | 5418 | 0.4118 | -0.1138 |
| SK-BR-3 | PHA-793887 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 2108 | 5418 | 0.3895 | -0.1578 |
| SK-BR-3 | PHA-793887 | 10 | uM | LJP6 | 72 | hr | 2543 | 1097 | 5418 | 0.2025 | -0.5377 |
| SK-BR-3 | QL-X-138 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 3613 | 5418 | 0.6680 | 0.3826 |
| SK-BR-3 | QL-X-138 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 3605 | 5418 | 0.6664 | 0.3795 |
| SK-BR-3 | QL-X-138 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 2880 | 5418 | 0.5321 | 0.1216 |
| SK-BR-3 | QL-X-138 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 2704 | 5418 | 0.4995 | 0.0583 |