LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | CP466722 | 10 | uM | LJP5 | 72 | hr | 2543 | 5693 | 5752 | 0.9897 | 0.9820 |
| SK-BR-3 | CP724714 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 3620 | 5752 | 0.6293 | 0.3495 |
| SK-BR-3 | CP724714 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 2873 | 5752 | 0.4995 | 0.1089 |
| SK-BR-3 | CP724714 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 2518 | 5752 | 0.4378 | -0.0085 |
| SK-BR-3 | CP724714 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 2800 | 5752 | 0.4867 | 0.0848 |
| SK-BR-3 | CP724714 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 2493 | 5752 | 0.4334 | -0.0169 |
| SK-BR-3 | CP724714 | 10 | uM | LJP5 | 72 | hr | 2543 | 2063 | 5752 | 0.3587 | -0.1634 |
| SK-BR-3 | Alvocidib | 0.04 | uM | LJP6 | 72 | hr | 2543 | 2952 | 5418 | 0.5448 | 0.1453 |
| SK-BR-3 | Alvocidib | 0.12 | uM | LJP6 | 72 | hr | 2543 | 1157 | 5418 | 0.2130 | -0.5153 |
| SK-BR-3 | Alvocidib | 0.37 | uM | LJP6 | 72 | hr | 2543 | 905 | 5418 | 0.1666 | -0.6127 |
| SK-BR-3 | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 2543 | 911 | 5418 | 0.1679 | -0.6102 |
| SK-BR-3 | Alvocidib | 3.33 | uM | LJP6 | 72 | hr | 2543 | 902 | 5418 | 0.1663 | -0.6137 |
| SK-BR-3 | Alvocidib | 10 | uM | LJP6 | 72 | hr | 2543 | 878 | 5418 | 0.1624 | -0.6228 |
| SK-BR-3 | GW843682X | 0.04 | uM | LJP6 | 72 | hr | 2543 | 5028 | 5418 | 0.9282 | 0.8679 |
| SK-BR-3 | GW843682X | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4493 | 5418 | 0.8297 | 0.6856 |
| SK-BR-3 | GW843682X | 0.37 | uM | LJP6 | 72 | hr | 2543 | 1972 | 5418 | 0.3641 | -0.2085 |
| SK-BR-3 | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1557 | 5418 | 0.2875 | -0.3625 |
| SK-BR-3 | GW843682X | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1433 | 5418 | 0.2646 | -0.4093 |
| SK-BR-3 | GW843682X | 10 | uM | LJP6 | 72 | hr | 2543 | 1353 | 5418 | 0.2499 | -0.4395 |
| SK-BR-3 | HG-5-113-01 | 0.04 | uM | LJP5 | 72 | hr | 2543 | 5446 | 5752 | 0.9467 | 0.9089 |
| SK-BR-3 | HG-5-113-01 | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5155 | 5752 | 0.8963 | 0.8221 |
| SK-BR-3 | HG-5-113-01 | 0.37 | uM | LJP5 | 72 | hr | 2543 | 4512 | 5752 | 0.7844 | 0.6269 |
| SK-BR-3 | HG-5-113-01 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 3242 | 5752 | 0.5637 | 0.2290 |
| SK-BR-3 | HG-5-113-01 | 3.33 | uM | LJP5 | 72 | hr | 2543 | 2049 | 5752 | 0.3563 | -0.1678 |
| SK-BR-3 | HG-5-113-01 | 10 | uM | LJP5 | 72 | hr | 2543 | 1703 | 5752 | 0.2961 | -0.2890 |