LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T AZD7762
1.11
uM
LJP6
 72
hr
 765 497 3101 0.1604 -0.1920
Hs 578T AZD7762
3.33
uM
LJP6
 72
hr
 765 466 3101 0.1504 -0.2176
Hs 578T AZD7762
10
uM
LJP6
 72
hr
 765 315 3101 0.1015 -0.3560
Hs 578T AZD8055
0.04
uM
LJP6
 72
hr
 765 1121 3101 0.3617 0.2086
Hs 578T AZD8055
0.12
uM
LJP6
 72
hr
 765 1030 3101 0.3322 0.1585
Hs 578T AZD8055
0.37
uM
LJP6
 72
hr
 765 1078 3101 0.3474 0.1839
Hs 578T AZD8055
1.11
uM
LJP6
 72
hr
 765 1035 3101 0.3335 0.1601
Hs 578T AZD8055
3.33
uM
LJP6
 72
hr
 765 829 3101 0.2677 0.0406
Hs 578T AZD8055
10
uM
LJP6
 72
hr
 765 510 3101 0.1650 -0.1859
Hs 578T Sorafenib
0.04
uM
LJP6
 72
hr
 765 3596 3101 1.1593 1.1519
Hs 578T Sorafenib
0.12
uM
LJP6
 72
hr
 765 3587 3101 1.1563 1.1491
Hs 578T Sorafenib
0.37
uM
LJP6
 72
hr
 765 3768 3101 1.2151 1.2026
Hs 578T Sorafenib
1.11
uM
LJP6
 72
hr
 765 3829 3101 1.2349 1.2203
Hs 578T Sorafenib
3.33
uM
LJP6
 72
hr
 765 3770 3101 1.2154 1.2028
Hs 578T Sorafenib
10
uM
LJP6
 72
hr
 765 2854 3101 0.9203 0.9189
Hs 578T CP466722
0.04
uM
LJP5
 72
hr
 765 3236 3148 1.0279 1.0270
Hs 578T CP466722
0.12
uM
LJP5
 72
hr
 765 3222 3148 1.0236 1.0230
Hs 578T CP466722
0.37
uM
LJP5
 72
hr
 765 3368 3148 1.0700 1.0672
Hs 578T CP466722
1.11
uM
LJP5
 72
hr
 765 3313 3148 1.0526 1.0508
Hs 578T CP466722
3.33
uM
LJP5
 72
hr
 765 3075 3148 0.9770 0.9770
Hs 578T CP466722
10
uM
LJP5
 72
hr
 765 2615 3148 0.8307 0.8262
Hs 578T CP724714
0.04
uM
LJP5
 72
hr
 765 3067 3148 0.9744 0.9746
Hs 578T CP724714
0.12
uM
LJP5
 72
hr
 765 3139 3148 0.9971 0.9969
Hs 578T CP724714
0.37
uM
LJP5
 72
hr
 765 3127 3148 0.9935 0.9934
Hs 578T CP724714
1.11
uM
LJP5
 72
hr
 765 3123 3148 0.9920 0.9921