LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 Withaferin A
0.12
uM
LJP5
 72
hr
 1334 3607 4033 0.8934 0.8617
BT-20 Withaferin A
0.12
uM
LJP6
 72
hr
 1334 4046 3925 1.0310 1.0394
BT-20 Withaferin A
0.37
uM
LJP5
 72
hr
 1334 2924 4033 0.7251 0.6346
BT-20 Withaferin A
0.37
uM
LJP6
 72
hr
 1334 3459 3925 0.8814 0.8437
BT-20 Withaferin A
1.11
uM
LJP5
 72
hr
 1334 708 4033 0.1760 -0.3277
BT-20 Withaferin A
1.11
uM
LJP6
 72
hr
 1334 1493 3925 0.3804 0.0724
BT-20 Withaferin A
3.33
uM
LJP5
 72
hr
 1334 647 4033 0.1605 -0.3650
BT-20 Withaferin A
3.33
uM
LJP6
 72
hr
 1334 504 3925 0.1285 -0.4650
BT-20 Withaferin A
10
uM
LJP5
 72
hr
 1334 865 4033 0.2145 -0.2383
BT-20 Withaferin A
10
uM
LJP6
 72
hr
 1334 771 3925 0.1963 -0.2993
Hs 578T Seliciclib
0.04
uM
LJP5
 72
hr
 765 3140 3148 0.9974 0.9974
Hs 578T Seliciclib
0.12
uM
LJP5
 72
hr
 765 3161 3148 1.0043 1.0041
Hs 578T Seliciclib
0.37
uM
LJP5
 72
hr
 765 3110 3148 0.9880 0.9880
Hs 578T Seliciclib
1.11
uM
LJP5
 72
hr
 765 3091 3148 0.9820 0.9818
Hs 578T Seliciclib
3.33
uM
LJP5
 72
hr
 765 3092 3148 0.9823 0.9822
Hs 578T Seliciclib
10
uM
LJP5
 72
hr
 765 2245 3148 0.7132 0.6947
Hs 578T AT-7519
0.04
uM
LJP6
 72
hr
 765 2849 3101 0.9193 0.9179
Hs 578T AT-7519
0.12
uM
LJP6
 72
hr
 765 2279 3101 0.7348 0.7168
Hs 578T AT-7519
0.37
uM
LJP6
 72
hr
 765 531 3101 0.1712 -0.1659
Hs 578T AT-7519
1.11
uM
LJP6
 72
hr
 765 445 3101 0.1436 -0.2353
Hs 578T AT-7519
3.33
uM
LJP6
 72
hr
 765 300 3101 0.0968 -0.3718
Hs 578T AT-7519
10
uM
LJP6
 72
hr
 765 266 3101 0.0862 -0.4158
Hs 578T AZD7762
0.04
uM
LJP6
 72
hr
 765 1116 3101 0.3600 0.2054
Hs 578T AZD7762
0.12
uM
LJP6
 72
hr
 765 632 3101 0.2040 -0.0903
Hs 578T AZD7762
0.37
uM
LJP6
 72
hr
 765 565 3101 0.1824 -0.1395