LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 YM 201636
1.11
uM
LJP5
 72
hr
 1334 3248 4033 0.8058 0.7470
BT-20 YM 201636
0.37
uM
LJP5
 72
hr
 1334 3883 4033 0.9638 0.9546
BT-20 YM 201636
0.12
uM
LJP5
 72
hr
 1334 4143 4033 1.0274 1.0343
BT-20 YM 201636
0.04
uM
LJP5
 72
hr
 1334 4177 4033 1.0363 1.0451
MDA-MB-231 ZSTK474
10
uM
LJP6
 72
hr
 1311 2522 4935 0.5113 0.4078
MDA-MB-231 ZSTK474
3.33
uM
LJP6
 72
hr
 1311 2945 4935 0.5971 0.5264
MDA-MB-231 ZSTK474
1.11
uM
LJP6
 72
hr
 1311 3595 4935 0.7285 0.6946
MDA-MB-231 ZSTK474
0.37
uM
LJP6
 72
hr
 1311 3694 4935 0.7486 0.7179
MDA-MB-231 ZSTK474
0.12
uM
LJP6
 72
hr
 1311 4180 4935 0.8471 0.8332
MDA-MB-231 ZSTK474
0.04
uM
LJP6
 72
hr
 1311 4440 4935 0.9000 0.8926
MCF 10A ZSTK474
0.04
uM
LJP6
 72
hr
 1694 10958 11217 0.9768 0.9828
Hs 578T ZSTK474
10
uM
LJP6
 72
hr
 765 805 3101 0.2597 0.0253
MCF 10A ZSTK474
0.12
uM
LJP6
 72
hr
 1694 9950 11217 0.8870 0.9138
MCF 10A ZSTK474
0.37
uM
LJP6
 72
hr
 1694 8257 11217 0.7361 0.7874
MCF 10A ZSTK474
1.11
uM
LJP6
 72
hr
 1694 5606 11217 0.4997 0.5499
MCF 10A ZSTK474
3.33
uM
LJP6
 72
hr
 1694 3867 11217 0.3445 0.3517
MCF 10A ZSTK474
10
uM
LJP6
 72
hr
 1694 2788 11217 0.2485 0.1997
Hs 578T ZSTK474
3.33
uM
LJP6
 72
hr
 765 1087 3101 0.3506 0.1901
Hs 578T ZSTK474
1.11
uM
LJP6
 72
hr
 765 1316 3101 0.4241 0.3072
Hs 578T ZSTK474
0.37
uM
LJP6
 72
hr
 765 1696 3101 0.5468 0.4827
Hs 578T ZSTK474
0.12
uM
LJP6
 72
hr
 765 2092 3101 0.6745 0.6455
Hs 578T ZSTK474
0.04
uM
LJP6
 72
hr
 765 2489 3101 0.8025 0.7933
SK-BR-3 ZSTK474
10
uM
LJP6
 72
hr
 2543 2048 5418 0.3781 -0.1806
BT-20 ZSTK474
10
uM
LJP6
 72
hr
 1334 1209 3925 0.3079 -0.0618
BT-20 ZSTK474
3.33
uM
LJP6
 72
hr
 1334 1881 3925 0.4788 0.2411