LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T AZD7762
10
uM
LJP6
 72
hr
 765 315 3101 0.1015 -0.3560
SK-BR-3 AZD7762
0.04
uM
LJP6
 72
hr
 2543 2030 5418 0.3747 -0.1872
MDA-MB-231 AZD7762
0.04
uM
LJP6
 72
hr
 1311 4468 4935 0.9055 0.8988
MDA-MB-231 AZD7762
0.12
uM
LJP6
 72
hr
 1311 2858 4935 0.5792 0.5030
MCF7 AZD7762
3.33
uM
LJP6
 72
hr
 1389 1098 5445 0.2015 -0.1148
MDA-MB-231 AZD7762
3.33
uM
LJP6
 72
hr
 1311 785 4935 0.1593 -0.2353
MDA-MB-231 AZD7762
10
uM
LJP6
 72
hr
 1311 716 4935 0.1452 -0.2722
MCF7 AZD7762
1.11
uM
LJP6
 72
hr
 1389 1327 5445 0.2444 -0.0227
BT-20 AZD7762
10
uM
LJP6
 72
hr
 1334 417 3925 0.1064 -0.5260
BT-20 AZD7762
3.33
uM
LJP6
 72
hr
 1334 1438 3925 0.3665 0.0491
MCF 10A AZD7762
0.12
uM
LJP6
 72
hr
 1694 7703 11217 0.6867 0.7424
Hs 578T AZD7762
3.33
uM
LJP6
 72
hr
 765 466 3101 0.1504 -0.2176
MCF 10A AZD7762
0.04
uM
LJP6
 72
hr
 1694 9157 11217 0.8162 0.8563
SK-BR-3 AZD8055
0.37
uM
LJP6
 72
hr
 2543 1782 5418 0.3289 -0.2789
MDA-MB-231 AZD8055
0.04
uM
LJP6
 72
hr
 1311 2919 4935 0.5917 0.5182
SK-BR-3 AZD8055
0.12
uM
LJP6
 72
hr
 2543 1763 5418 0.3254 -0.2859
Hs 578T AZD8055
0.04
uM
LJP6
 72
hr
 765 1121 3101 0.3617 0.2086
Hs 578T AZD8055
1.11
uM
LJP6
 72
hr
 765 1035 3101 0.3335 0.1601
SK-BR-3 AZD8055
1.11
uM
LJP6
 72
hr
 2543 1906 5418 0.3518 -0.2329
MCF7 AZD8055
10
uM
LJP6
 72
hr
 1389 1120 5445 0.2052 -0.1075
MDA-MB-231 AZD8055
0.12
uM
LJP6
 72
hr
 1311 2249 4935 0.4557 0.3244
MCF7 AZD8055
0.04
uM
LJP6
 72
hr
 1389 1577 5445 0.2898 0.0624
MCF 10A AZD8055
10
uM
LJP6
 72
hr
 1694 2374 11217 0.2117 0.1313
BT-20 AZD8055
0.04
uM
LJP6
 72
hr
 1334 2367 3925 0.6035 0.4440
BT-20 AZD8055
0.12
uM
LJP6
 72
hr
 1334 1948 3925 0.4964 0.2749