LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T AZD-6482
10
uM
LJP5
 72
hr
 765 1071 3148 0.3403 0.1791
Hs 578T AZD-6482
3.33
uM
LJP5
 72
hr
 765 2022 3148 0.6425 0.6100
Hs 578T AZD7762
0.04
uM
LJP6
 72
hr
 765 1116 3101 0.3600 0.2054
MCF7 AZD7762
0.37
uM
LJP6
 72
hr
 1389 1519 5445 0.2789 0.0452
MCF7 AZD7762
0.12
uM
LJP6
 72
hr
 1389 1691 5445 0.3110 0.1047
MDA-MB-231 AZD7762
0.12
uM
LJP6
 72
hr
 1311 2858 4935 0.5792 0.5030
Hs 578T AZD7762
0.12
uM
LJP6
 72
hr
 765 632 3101 0.2040 -0.0903
SK-BR-3 AZD7762
0.04
uM
LJP6
 72
hr
 2543 2030 5418 0.3747 -0.1872
SK-BR-3 AZD7762
0.37
uM
LJP6
 72
hr
 2543 1559 5418 0.2877 -0.3621
MCF7 AZD7762
0.04
uM
LJP6
 72
hr
 1389 1987 5445 0.3659 0.2000
Hs 578T AZD7762
0.37
uM
LJP6
 72
hr
 765 565 3101 0.1824 -0.1395
MDA-MB-231 AZD7762
0.37
uM
LJP6
 72
hr
 1311 2430 4935 0.4926 0.3808
SK-BR-3 AZD7762
0.12
uM
LJP6
 72
hr
 2543 1690 5418 0.3120 -0.3129
MCF7 AZD7762
3.33
uM
LJP6
 72
hr
 1389 1098 5445 0.2015 -0.1148
BT-20 AZD7762
0.04
uM
LJP6
 72
hr
 1334 4096 3925 1.0433 1.0540
MCF7 AZD7762
10
uM
LJP6
 72
hr
 1389 771 5445 0.1412 -0.2608
MDA-MB-231 AZD7762
3.33
uM
LJP6
 72
hr
 1311 785 4935 0.1593 -0.2353
MDA-MB-231 AZD7762
1.11
uM
LJP6
 72
hr
 1311 1235 4935 0.2504 -0.0309
SK-BR-3 AZD7762
1.11
uM
LJP6
 72
hr
 2543 1345 5418 0.2480 -0.4431
BT-20 AZD7762
3.33
uM
LJP6
 72
hr
 1334 1438 3925 0.3665 0.0491
MCF 10A AZD7762
3.33
uM
LJP6
 72
hr
 1694 3091 11217 0.2757 0.2465
BT-20 AZD7762
0.37
uM
LJP6
 72
hr
 1334 3122 3925 0.7952 0.7260
MDA-MB-231 AZD7762
0.04
uM
LJP6
 72
hr
 1311 4468 4935 0.9055 0.8988
MDA-MB-231 AZD7762
10
uM
LJP6
 72
hr
 1311 716 4935 0.1452 -0.2722
BT-20 AZD7762
0.12
uM
LJP6
 72
hr
 1334 3628 3925 0.9241 0.9006