LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 Mitoxantrone
3.33
uM
LJP5
 72
hr
 1334 698 4033 0.1729 -0.3347
BT-20 Mitoxantrone
3.33
uM
LJP6
 72
hr
 1334 597 3925 0.1523 -0.4037
SK-BR-3 WZ3105
3.33
uM
LJP5
 72
hr
 2543 1303 5752 0.2266 -0.4336
MCF7 HG-5-113-01
3.33
uM
LJP5
 72
hr
 1389 1646 5905 0.2786 0.0840
MCF 10A XMD11-50
3.33
uM
LJP6
 72
hr
 1694 5322 11217 0.4745 0.5204
BT-20 Seliciclib
3.33
uM
LJP5
 72
hr
 1334 3442 4033 0.8529 0.8091
BT-20 Radicicol
3.33
uM
LJP5
 72
hr
 1334 954 4033 0.2367 -0.1897
BT-20 Radicicol
3.33
uM
LJP6
 72
hr
 1334 980 3925 0.2498 -0.1800
SK-BR-3 Seliciclib
3.33
uM
LJP5
 72
hr
 2543 4738 5752 0.8238 0.6963
MDA-MB-231 BI-2536
3.33
uM
LJP6
 72
hr
 1311 1296 4935 0.2626 -0.0073
MCF 10A R406
3.33
uM
LJP6
 72
hr
 1694 10161 11217 0.9062 0.9284
MCF7 XMD11-50
3.33
uM
LJP6
 72
hr
 1389 2022 5445 0.3699 0.2037
MDA-MB-231 Withaferin A
3.33
uM
LJP6
 72
hr
 1311 810 4935 0.1642 -0.2233
BT-20 Withaferin A
3.33
uM
LJP5
 72
hr
 1334 647 4033 0.1605 -0.3650
BT-20 Withaferin A
3.33
uM
LJP6
 72
hr
 1334 504 3925 0.1285 -0.4650