LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T GW843682X
0.12
uM
LJP6
 72
hr
 765 2379 3101 0.7670 0.7533
Hs 578T GW843682X
0.37
uM
LJP6
 72
hr
 765 792 3101 0.2556 0.0175
Hs 578T GW843682X
3.33
uM
LJP6
 72
hr
 765 392 3101 0.1265 -0.2817
Hs 578T GW843682X
10
uM
LJP6
 72
hr
 765 450 3101 0.1453 -0.2306
Hs 578T HG-5-113-01
1.11
uM
LJP5
 72
hr
 765 1776 3148 0.5642 0.5105
Hs 578T HG-5-113-01
3.33
uM
LJP5
 72
hr
 765 894 3148 0.2841 0.0787
Hs 578T HG-5-88-01
0.04
uM
LJP6
 72
hr
 765 2930 3101 0.9448 0.9445
Hs 578T HG-5-88-01
0.12
uM
LJP6
 72
hr
 765 3009 3101 0.9702 0.9703
Hs 578T HG-5-88-01
3.33
uM
LJP6
 72
hr
 765 2620 3101 0.8445 0.8392
Hs 578T HG-5-88-01
10
uM
LJP6
 72
hr
 765 2098 3101 0.6765 0.6480
Hs 578T HG-6-64-01
0.12
uM
LJP6
 72
hr
 765 3351 3101 1.0806 1.0782
Hs 578T HG-6-64-01
0.37
uM
LJP6
 72
hr
 765 2937 3101 0.9467 0.9456
Hs 578T Seliciclib
0.04
uM
LJP5
 72
hr
 765 3140 3148 0.9974 0.9974
Hs 578T Seliciclib
0.12
uM
LJP5
 72
hr
 765 3161 3148 1.0043 1.0041
Hs 578T Seliciclib
1.11
uM
LJP5
 72
hr
 765 3091 3148 0.9820 0.9818
Hs 578T Seliciclib
3.33
uM
LJP5
 72
hr
 765 3092 3148 0.9823 0.9822
Hs 578T AT-7519
0.12
uM
LJP6
 72
hr
 765 2279 3101 0.7348 0.7168
Hs 578T AT-7519
0.37
uM
LJP6
 72
hr
 765 531 3101 0.1712 -0.1659
Hs 578T AT-7519
3.33
uM
LJP6
 72
hr
 765 300 3101 0.0968 -0.3718
Hs 578T AT-7519
10
uM
LJP6
 72
hr
 765 266 3101 0.0862 -0.4158
Hs 578T AZD7762
1.11
uM
LJP6
 72
hr
 765 497 3101 0.1604 -0.1920
Hs 578T AZD7762
3.33
uM
LJP6
 72
hr
 765 466 3101 0.1504 -0.2176
Hs 578T AZD8055
0.04
uM
LJP6
 72
hr
 765 1121 3101 0.3617 0.2086
Hs 578T Neratinib
0.37
uM
LJP5
 72
hr
 765 2248 3148 0.7143 0.6952
Hs 578T Neratinib
0.12
uM
LJP5
 72
hr
 765 2591 3148 0.8232 0.8180