LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T GSK1904529A
0.12
uM
LJP6
 72
hr
 765 2929 3101 0.9447 0.9445
Hs 578T GSK1904529A
0.37
uM
LJP6
 72
hr
 765 3046 3101 0.9819 0.9818
Hs 578T Linsitinib
0.04
uM
LJP5
 72
hr
 765 3175 3148 1.0087 1.0084
Hs 578T Linsitinib
0.12
uM
LJP5
 72
hr
 765 3166 3148 1.0059 1.0057
Hs 578T Linsitinib
1.11
uM
LJP5
 72
hr
 765 3223 3148 1.0238 1.0230
Hs 578T Linsitinib
3.33
uM
LJP5
 72
hr
 765 3097 3148 0.9840 0.9842
Hs 578T Ruxolitinib
0.12
uM
LJP5
 72
hr
 765 3194 3148 1.0146 1.0142
Hs 578T Ruxolitinib
0.37
uM
LJP5
 72
hr
 765 3131 3148 0.9946 0.9946
Hs 578T Ruxolitinib
3.33
uM
LJP5
 72
hr
 765 2778 3148 0.8826 0.8811
Hs 578T Ruxolitinib
10
uM
LJP5
 72
hr
 765 2151 3148 0.6833 0.6594
Hs 578T Seliciclib
0.04
uM
LJP5
 72
hr
 765 3140 3148 0.9974 0.9974
Hs 578T Seliciclib
0.12
uM
LJP5
 72
hr
 765 3161 3148 1.0043 1.0041
Hs 578T Seliciclib
1.11
uM
LJP5
 72
hr
 765 3091 3148 0.9820 0.9818
Hs 578T Seliciclib
3.33
uM
LJP5
 72
hr
 765 3092 3148 0.9823 0.9822
Hs 578T AT-7519
0.12
uM
LJP6
 72
hr
 765 2279 3101 0.7348 0.7168
Hs 578T AT-7519
0.37
uM
LJP6
 72
hr
 765 531 3101 0.1712 -0.1659
Hs 578T AT-7519
3.33
uM
LJP6
 72
hr
 765 300 3101 0.0968 -0.3718
Hs 578T AT-7519
10
uM
LJP6
 72
hr
 765 266 3101 0.0862 -0.4158
Hs 578T AZD7762
1.11
uM
LJP6
 72
hr
 765 497 3101 0.1604 -0.1920
Hs 578T AZD7762
3.33
uM
LJP6
 72
hr
 765 466 3101 0.1504 -0.2176
Hs 578T AZD8055
0.04
uM
LJP6
 72
hr
 765 1121 3101 0.3617 0.2086
Hs 578T AZD8055
0.12
uM
LJP6
 72
hr
 765 1030 3101 0.3322 0.1585
Hs 578T AZD8055
3.33
uM
LJP6
 72
hr
 765 829 3101 0.2677 0.0406
Hs 578T Fedratinib
0.37
uM
LJP5
 72
hr
 765 2853 3148 0.9063 0.9057
Hs 578T Fedratinib
0.12
uM
LJP5
 72
hr
 765 3148 3148 1.0000 0.9999