LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Pictilisib
0.37
uM
LJP6
 72
hr
 765 1791 3101 0.5775 0.5238
Hs 578T Pictilisib
10
uM
LJP6
 72
hr
 765 1063 3101 0.3428 0.1769
Hs 578T PD184352
0.04
uM
LJP5
 72
hr
 765 2390 3148 0.7592 0.7471
Hs 578T PD184352
0.37
uM
LJP5
 72
hr
 765 1843 3148 0.5856 0.5387
Hs 578T PD184352
1.11
uM
LJP5
 72
hr
 765 1637 3148 0.5201 0.4514
Hs 578T PLX-4720
0.12
uM
LJP5
 72
hr
 765 3499 3148 1.1116 1.1062
Hs 578T PLX-4720
0.37
uM
LJP5
 72
hr
 765 3751 3148 1.1915 1.1790
Hs 578T PLX-4720
3.33
uM
LJP5
 72
hr
 765 3306 3148 1.0503 1.0484
Hs 578T PLX-4720
10
uM
LJP5
 72
hr
 765 2248 3148 0.7141 0.6955
Hs 578T Lapatinib
0.37
uM
LJP6
 72
hr
 765 3048 3101 0.9828 0.9829
Hs 578T Lapatinib
1.11
uM
LJP6
 72
hr
 765 3066 3101 0.9888 0.9888
Hs 578T Lapatinib
10
uM
LJP6
 72
hr
 765 2210 3101 0.7123 0.6903
Hs 578T Sirolimus
0.04
uM
LJP6
 72
hr
 765 1832 3101 0.5906 0.5409
Hs 578T Sirolimus
10
uM
LJP6
 72
hr
 765 1779 3101 0.5736 0.5188
Hs 578T ZSTK474
0.04
uM
LJP6
 72
hr
 765 2489 3101 0.8025 0.7933
Hs 578T ZSTK474
0.37
uM
LJP6
 72
hr
 765 1696 3101 0.5468 0.4827
Hs 578T ZSTK474
1.11
uM
LJP6
 72
hr
 765 1316 3101 0.4241 0.3072
Hs 578T BX-912
0.04
uM
LJP5
 72
hr
 765 3105 3148 0.9863 0.9865
Hs 578T BX-912
0.12
uM
LJP5
 72
hr
 765 2929 3148 0.9305 0.9305
Hs 578T BX-912
1.11
uM
LJP5
 72
hr
 765 1515 3148 0.4812 0.3971
Hs 578T BX-912
3.33
uM
LJP5
 72
hr
 765 915 3148 0.2908 0.0898
Hs 578T Selumetinib
0.37
uM
LJP6
 72
hr
 765 1601 3101 0.5162 0.4415
Hs 578T Selumetinib
1.11
uM
LJP6
 72
hr
 765 1484 3101 0.4785 0.3883
Hs 578T AZD-6482
1.11
uM
LJP5
 72
hr
 765 2358 3148 0.7491 0.7360
Hs 578T AZD-6482
0.37
uM
LJP5
 72
hr
 765 2629 3148 0.8353 0.8312