LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 AZD 5438
10
uM
LJP6
 72
hr
 1389 297 5445 0.0548 -0.5439
MCF 10A Alvocidib
1.11
uM
LJP6
 72
hr
 1694 299 11217 0.0267 -0.4731
MCF 10A Alvocidib
0.37
uM
LJP6
 72
hr
 1694 300 11217 0.0268 -0.4707
Hs 578T AT-7519
3.33
uM
LJP6
 72
hr
 765 300 3101 0.0968 -0.3718
MCF7 CGP60474
10
uM
LJP6
 72
hr
 1389 300 5445 0.0552 -0.5407
Hs 578T Foretinib
10
uM
LJP5
 72
hr
 765 302 3148 0.0959 -0.3659
MCF 10A CGP60474
0.12
uM
LJP6
 72
hr
 1694 306 11217 0.0273 -0.4672
MCF 10A SNS-032
3.33
uM
LJP6
 72
hr
 1694 308 11217 0.0275 -0.4650
MCF 10A SNS-032
1.11
uM
LJP6
 72
hr
 1694 309 11217 0.0276 -0.4641
BT-20 GSK1059615
10
uM
LJP6
 72
hr
 1334 312 3925 0.0796 -0.6087
MCF 10A AT-7519
3.33
uM
LJP6
 72
hr
 1694 314 11217 0.0280 -0.4612
Hs 578T AZD7762
10
uM
LJP6
 72
hr
 765 315 3101 0.1015 -0.3560
BT-20 Alvocidib
10
uM
LJP6
 72
hr
 1334 317 3925 0.0807 -0.6034
Hs 578T Fedratinib
10
uM
LJP5
 72
hr
 765 321 3148 0.1021 -0.3478
Hs 578T A443654
3.33
uM
LJP6
 72
hr
 765 321 3101 0.1036 -0.3494
Hs 578T Withaferin A
10
uM
LJP5
 72
hr
 765 322 3148 0.1025 -0.3466
Hs 578T Withaferin A
10
uM
LJP6
 72
hr
 765 326 3101 0.1050 -0.3465
BT-20 CGP60474
10
uM
LJP5
 72
hr
 1334 330 4033 0.0819 -0.5837
Hs 578T Buparlisib
10
uM
LJP5
 72
hr
 765 331 3148 0.1051 -0.3367
MCF 10A Alvocidib
10
uM
LJP6
 72
hr
 1694 336 11217 0.0299 -0.4480
MCF7 CGP60474
10
uM
LJP5
 72
hr
 1389 343 5905 0.0581 -0.4884
Hs 578T Geldanamycin
10
uM
LJP5
 72
hr
 765 344 3148 0.1095 -0.3253
MCF7 AT-7519
10
uM
LJP6
 72
hr
 1389 344 5445 0.0635 -0.5080
MCF7 Mitoxantrone
10
uM
LJP6
 72
hr
 1389 345 5445 0.0630 -0.5105
Hs 578T CGP60474
0.04
uM
LJP6
 72
hr
 765 346 3101 0.1119 -0.3251