LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | GSK1059615 | 10 | uM | LJP6 | 72 | hr | 2543 | 1016 | 5418 | 0.1876 | -0.5690 |
| BT-20 | Alvocidib | 3.33 | uM | LJP6 | 72 | hr | 1334 | 364 | 3925 | 0.0928 | -0.5663 |
| SK-BR-3 | A443654 | 10 | uM | LJP6 | 72 | hr | 2543 | 1031 | 5418 | 0.1903 | -0.5635 |
| BT-20 | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 1334 | 370 | 3925 | 0.0942 | -0.5615 |
| SK-BR-3 | Omipalisib | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1036 | 5418 | 0.1914 | -0.5613 |
| SK-BR-3 | Mitoxantrone | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1043 | 5418 | 0.1922 | -0.5589 |
| BT-20 | CGP60474 | 3.33 | uM | LJP5 | 72 | hr | 1334 | 367 | 4033 | 0.0912 | -0.5545 |
| SK-BR-3 | CGP60474 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1058 | 5418 | 0.1952 | -0.5529 |
| SK-BR-3 | SNS-032 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1077 | 5418 | 0.1991 | -0.5453 |
| SK-BR-3 | PF562271 | 10 | uM | LJP6 | 72 | hr | 2543 | 1079 | 5418 | 0.1994 | -0.5446 |
| MCF7 | AZD 5438 | 10 | uM | LJP6 | 72 | hr | 1389 | 297 | 5445 | 0.0548 | -0.5439 |
| BT-20 | Mitoxantrone | 10 | uM | LJP5 | 72 | hr | 1334 | 382 | 4033 | 0.0947 | -0.5439 |
| BT-20 | SNS-032 | 3.33 | uM | LJP6 | 72 | hr | 1334 | 394 | 3925 | 0.1004 | -0.5434 |
| BT-20 | WZ3105 | 10 | uM | LJP5 | 72 | hr | 1334 | 385 | 4033 | 0.0956 | -0.5412 |
| BT-20 | CGP60474 | 1.11 | uM | LJP6 | 72 | hr | 1334 | 397 | 3925 | 0.1012 | -0.5410 |
| SK-BR-3 | WZ-4-145 | 10 | uM | LJP6 | 72 | hr | 2543 | 1089 | 5418 | 0.2011 | -0.5408 |
| MCF7 | CGP60474 | 10 | uM | LJP6 | 72 | hr | 1389 | 300 | 5445 | 0.0552 | -0.5407 |
| SK-BR-3 | PHA-793887 | 10 | uM | LJP6 | 72 | hr | 2543 | 1097 | 5418 | 0.2025 | -0.5377 |
| BT-20 | AZD 5438 | 10 | uM | LJP6 | 72 | hr | 1334 | 407 | 3925 | 0.1038 | -0.5342 |
| SK-BR-3 | CGP60474 | 10 | uM | LJP5 | 72 | hr | 2543 | 1045 | 5752 | 0.1817 | -0.5302 |
| SK-BR-3 | Geldanamycin | 10 | uM | LJP6 | 72 | hr | 2543 | 1120 | 5418 | 0.2066 | -0.5290 |
| BT-20 | AZD7762 | 10 | uM | LJP6 | 72 | hr | 1334 | 417 | 3925 | 0.1064 | -0.5260 |
| BT-20 | SNS-032 | 10 | uM | LJP6 | 72 | hr | 1334 | 422 | 3925 | 0.1076 | -0.5238 |
| BT-20 | CGP60474 | 0.37 | uM | LJP5 | 72 | hr | 1334 | 410 | 4033 | 0.1017 | -0.5232 |
| MCF7 | Mitoxantrone | 10 | uM | LJP5 | 72 | hr | 1389 | 296 | 5905 | 0.0502 | -0.5229 |