LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T PHA-793887
0.37
uM
LJP6
 72
hr
 765 1113 3101 0.3591 0.2043
Hs 578T PHA-793887
1.11
uM
LJP6
 72
hr
 765 790 3101 0.2549 0.0162
Hs 578T PHA-793887
3.33
uM
LJP6
 72
hr
 765 619 3101 0.1999 -0.1000
Hs 578T PHA-793887
10
uM
LJP6
 72
hr
 765 397 3101 0.1282 -0.2777
Hs 578T QL-X-138
0.04
uM
LJP6
 72
hr
 765 2546 3101 0.8210 0.8138
Hs 578T QL-X-138
0.12
uM
LJP6
 72
hr
 765 2301 3101 0.7420 0.7253
Hs 578T QL-X-138
0.37
uM
LJP6
 72
hr
 765 2050 3101 0.6611 0.6294
Hs 578T QL-X-138
1.11
uM
LJP6
 72
hr
 765 1711 3101 0.5517 0.4897
Hs 578T QL-X-138
3.33
uM
LJP6
 72
hr
 765 1463 3101 0.4717 0.3782
Hs 578T QL-X-138
10
uM
LJP6
 72
hr
 765 572 3101 0.1846 -0.1344
Hs 578T QL-XII-47
0.04
uM
LJP6
 72
hr
 765 2960 3101 0.9541 0.9536
Hs 578T QL-XII-47
0.12
uM
LJP6
 72
hr
 765 2805 3101 0.9043 0.9028
Hs 578T QL-XII-47
0.37
uM
LJP6
 72
hr
 765 2539 3101 0.8183 0.8104
Hs 578T QL-XII-47
1.11
uM
LJP6
 72
hr
 765 2041 3101 0.6578 0.6245
Hs 578T QL-XII-47
3.33
uM
LJP6
 72
hr
 765 1207 3101 0.3891 0.2528
Hs 578T QL-XII-47
10
uM
LJP6
 72
hr
 765 412 3101 0.1329 -0.2644
Hs 578T Torin1
0.04
uM
LJP6
 72
hr
 765 1096 3101 0.3534 0.1949
MDA-MB-231 Mitoxantrone
0.04
uM
LJP6
 72
hr
 1311 1081 4935 0.2192 -0.0969
Hs 578T Torin1
0.12
uM
LJP6
 72
hr
 765 974 3101 0.3143 0.1266
MDA-MB-231 Mitoxantrone
0.12
uM
LJP6
 72
hr
 1311 1073 4935 0.2174 -0.1001
Hs 578T Torin1
0.37
uM
LJP6
 72
hr
 765 867 3101 0.2797 0.0640
MDA-MB-231 Mitoxantrone
0.37
uM
LJP6
 72
hr
 1311 992 4935 0.2011 -0.1359
Hs 578T Torin1
1.11
uM
LJP6
 72
hr
 765 781 3101 0.2520 0.0102
MDA-MB-231 Mitoxantrone
1.11
uM
LJP6
 72
hr
 1311 904 4935 0.1833 -0.1770
Hs 578T Torin1
3.33
uM
LJP6
 72
hr
 765 698 3101 0.2252 -0.0443