LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 Pictilisib
0.37
uM
LJP6
 72
hr
 1334 2996 3925 0.7639 0.6790
BT-20 Pictilisib
10
uM
LJP6
 72
hr
 1334 1307 3925 0.3333 -0.0146
BT-20 PD184352
0.04
uM
LJP5
 72
hr
 1334 4104 4033 1.0175 1.0213
BT-20 PD184352
0.37
uM
LJP5
 72
hr
 1334 4079 4033 1.0116 1.0145
BT-20 PD184352
1.11
uM
LJP5
 72
hr
 1334 3994 4033 0.9907 0.9885
BT-20 PLX-4720
0.12
uM
LJP5
 72
hr
 1334 4044 4033 1.0039 1.0049
BT-20 PLX-4720
0.37
uM
LJP5
 72
hr
 1334 4021 4033 0.9973 0.9969
BT-20 PLX-4720
3.33
uM
LJP5
 72
hr
 1334 3389 4033 0.8410 0.7946
BT-20 PLX-4720
10
uM
LJP5
 72
hr
 1334 2460 4033 0.6103 0.4672
BT-20 Lapatinib
0.37
uM
LJP6
 72
hr
 1334 3896 3925 0.9925 0.9898
BT-20 Lapatinib
1.11
uM
LJP6
 72
hr
 1334 4110 3925 1.0473 1.0603
BT-20 Lapatinib
10
uM
LJP6
 72
hr
 1334 3645 3925 0.9287 0.9070
BT-20 Sirolimus
0.04
uM
LJP6
 72
hr
 1334 2522 3925 0.6426 0.5052
BT-20 Sirolimus
10
uM
LJP6
 72
hr
 1334 2748 3925 0.7002 0.5907
BT-20 ZSTK474
0.04
uM
LJP6
 72
hr
 1334 3845 3925 0.9790 0.9708
BT-20 ZSTK474
0.37
uM
LJP6
 72
hr
 1334 3685 3925 0.9387 0.9199
BT-20 ZSTK474
1.11
uM
LJP6
 72
hr
 1334 2264 3925 0.5775 0.4007
BT-20 BX-912
0.04
uM
LJP5
 72
hr
 1334 3739 4033 0.9270 0.9067
BT-20 BX-912
0.12
uM
LJP5
 72
hr
 1334 3931 4033 0.9751 0.9688
BT-20 BX-912
1.11
uM
LJP5
 72
hr
 1334 3950 4033 0.9794 0.9736
BT-20 BX-912
3.33
uM
LJP5
 72
hr
 1334 3578 4033 0.8876 0.8559
BT-20 Selumetinib
0.37
uM
LJP6
 72
hr
 1334 3848 3925 0.9801 0.9729
BT-20 Selumetinib
1.11
uM
LJP6
 72
hr
 1334 3880 3925 0.9882 0.9838
BT-20 AZD-6482
1.11
uM
LJP5
 72
hr
 1334 2794 4033 0.6937 0.5901
BT-20 AZD-6482
0.37
uM
LJP5
 72
hr
 1334 3487 4033 0.8649 0.8263