LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 ZSTK474
0.12
uM
LJP6
 72
hr
 1334 3917 3925 0.9979 0.9970
SK-BR-3 ZSTK474
0.37
uM
LJP6
 72
hr
 2543 2667 5418 0.4932 0.0463
SK-BR-3 ZSTK474
3.33
uM
LJP6
 72
hr
 2543 2036 5418 0.3760 -0.1846
SK-BR-3 ZSTK474
1.11
uM
LJP6
 72
hr
 2543 2252 5418 0.4157 -0.1061
SK-BR-3 ZSTK474
0.04
uM
LJP6
 72
hr
 2543 5056 5418 0.9338 0.8795
MCF7 ZSTK474
0.04
uM
LJP6
 72
hr
 1389 4300 5445 0.7900 0.7742
SK-BR-3 ZSTK474
0.12
uM
LJP6
 72
hr
 2543 4005 5418 0.7398 0.5179
Hs 578T ZSTK474
0.04
uM
LJP6
 72
hr
 765 2489 3101 0.8025 0.7933
Hs 578T ZSTK474
0.12
uM
LJP6
 72
hr
 765 2092 3101 0.6745 0.6455
MDA-MB-231 ZSTK474
0.37
uM
LJP6
 72
hr
 1311 3694 4935 0.7486 0.7179
MCF7 ZSTK474
10
uM
LJP6
 72
hr
 1389 1515 5445 0.2791 0.0454
MDA-MB-231 YM 201636
0.37
uM
LJP5
 72
hr
 1311 4674 5079 0.9203 0.9167
MDA-MB-231 YM 201636
1.11
uM
LJP5
 72
hr
 1311 4030 5079 0.7937 0.7763
MCF7 YM 201636
10
uM
LJP5
 72
hr
 1389 1595 5905 0.2699 0.0675
MDA-MB-231 YM 201636
3.33
uM
LJP5
 72
hr
 1311 3739 5079 0.7361 0.7094
MDA-MB-231 YM 201636
10
uM
LJP5
 72
hr
 1311 1386 5079 0.2731 0.0286
BT-20 YM 201636
1.11
uM
LJP5
 72
hr
 1334 3248 4033 0.8058 0.7470
BT-20 YM 201636
0.12
uM
LJP5
 72
hr
 1334 4143 4033 1.0274 1.0343
BT-20 YM 201636
0.37
uM
LJP5
 72
hr
 1334 3883 4033 0.9638 0.9546
BT-20 YM 201636
3.33
uM
LJP5
 72
hr
 1334 2784 4033 0.6907 0.5860
BT-20 YM 201636
10
uM
LJP5
 72
hr
 1334 1319 4033 0.3273 -0.0087
SK-BR-3 YM 201636
10
uM
LJP5
 72
hr
 2543 3011 5752 0.5236 0.1541
SK-BR-3 YM 201636
3.33
uM
LJP5
 72
hr
 2543 5005 5752 0.8701 0.7770
MDA-MB-231 YM 201636
0.12
uM
LJP5
 72
hr
 1311 5101 5079 1.0046 1.0037
MCF7 YM 201636
0.04
uM
LJP5
 72
hr
 1389 6388 5905 1.0823 1.0775