LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T XL147
0.12
uM
LJP5
 72
hr
 765 3068 3148 0.9748 0.9750
MCF 10A XL147
10
uM
LJP5
 72
hr
 1694 5776 11103 0.5203 0.5716
MDA-MB-231 WZ-4-145
0.04
uM
LJP6
 72
hr
 1311 4364 4935 0.8841 0.8746
MDA-MB-231 WZ-4-145
0.12
uM
LJP6
 72
hr
 1311 4569 4935 0.9258 0.9209
MCF7 WZ-4-145
1.11
uM
LJP6
 72
hr
 1389 2885 5445 0.5306 0.4496
MCF7 WZ-4-145
3.33
uM
LJP6
 72
hr
 1389 2662 5445 0.4893 0.3909
MCF7 WZ-4-145
0.37
uM
LJP6
 72
hr
 1389 3794 5445 0.6957 0.6618
MCF7 WZ-4-145
10
uM
LJP6
 72
hr
 1389 579 5445 0.1064 -0.3595
MCF7 WZ-4-145
0.04
uM
LJP6
 72
hr
 1389 3933 5445 0.7218 0.6937
MCF7 WZ-4-145
0.12
uM
LJP6
 72
hr
 1389 4235 5445 0.7766 0.7572
MDA-MB-231 WZ-4-145
0.37
uM
LJP6
 72
hr
 1311 4472 4935 0.9060 0.8991
Hs 578T WZ-4-145
0.37
uM
LJP6
 72
hr
 765 1915 3101 0.6173 0.5750
Hs 578T WZ-4-145
0.12
uM
LJP6
 72
hr
 765 2079 3101 0.6701 0.6393
Hs 578T WZ-4-145
1.11
uM
LJP6
 72
hr
 765 1579 3101 0.5090 0.4313
Hs 578T WZ-4-145
0.04
uM
LJP6
 72
hr
 765 2191 3101 0.7063 0.6834
Hs 578T WZ-4-145
3.33
uM
LJP6
 72
hr
 765 1509 3101 0.4866 0.4000
Hs 578T WZ-4-145
10
uM
LJP6
 72
hr
 765 713 3101 0.2301 -0.0341
SK-BR-3 WZ-4-145
3.33
uM
LJP6
 72
hr
 2543 2737 5418 0.5053 0.0692
SK-BR-3 WZ-4-145
0.04
uM
LJP6
 72
hr
 2543 3377 5418 0.6233 0.2960
SK-BR-3 WZ-4-145
0.12
uM
LJP6
 72
hr
 2543 3543 5418 0.6538 0.3537
SK-BR-3 WZ-4-145
1.11
uM
LJP6
 72
hr
 2543 2903 5418 0.5356 0.1275
SK-BR-3 WZ-4-145
0.37
uM
LJP6
 72
hr
 2543 3449 5418 0.6366 0.3216
MCF 10A WZ-4-145
3.33
uM
LJP6
 72
hr
 1694 8411 11217 0.7500 0.7997
MCF 10A WZ-4-145
10
uM
LJP6
 72
hr
 1694 2277 11217 0.2029 0.1139
BT-20 WZ-4-145
10
uM
LJP6
 72
hr
 1334 2361 3925 0.6015 0.4427