LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Gefitinib
3.33
uM
LJP6
 72
hr
 1311 4967 4935 1.0066 1.0067
MDA-MB-231 Gefitinib
10
uM
LJP6
 72
hr
 1311 4569 4935 0.9259 0.9210
MDA-MB-231 Nilotinib
0.04
uM
LJP5
 72
hr
 1311 4981 5079 0.9808 0.9802
MDA-MB-231 Nilotinib
0.12
uM
LJP5
 72
hr
 1311 5066 5079 0.9976 0.9975
MDA-MB-231 Nilotinib
0.37
uM
LJP5
 72
hr
 1311 4736 5079 0.9326 0.9295
MDA-MB-231 Nilotinib
1.11
uM
LJP5
 72
hr
 1311 4634 5079 0.9126 0.9085
MDA-MB-231 Nilotinib
3.33
uM
LJP5
 72
hr
 1311 4618 5079 0.9095 0.9050
MDA-MB-231 Nilotinib
10
uM
LJP5
 72
hr
 1311 1162 5079 0.2288 -0.0608
MDA-MB-231 JNK-9L
0.04
uM
LJP6
 72
hr
 1311 4136 4935 0.8382 0.8234
MDA-MB-231 JNK-9L
0.12
uM
LJP6
 72
hr
 1311 3804 4935 0.7706 0.7448
MDA-MB-231 JNK-9L
0.37
uM
LJP6
 72
hr
 1311 2934 4935 0.5947 0.5233
MDA-MB-231 JNK-9L
1.11
uM
LJP6
 72
hr
 1311 1674 4935 0.3393 0.1362
MDA-MB-231 JNK-9L
3.33
uM
LJP6
 72
hr
 1311 1100 4935 0.2230 -0.0880
MDA-MB-231 JNK-9L
10
uM
LJP6
 72
hr
 1311 960 4935 0.1945 -0.1508
MDA-MB-231 PD0325901
0.04
uM
LJP5
 72
hr
 1311 3265 5079 0.6429 0.5949
MDA-MB-231 PD0325901
0.04
uM
LJP6
 72
hr
 1311 3157 4935 0.6399 0.5835
MDA-MB-231 PD0325901
0.12
uM
LJP5
 72
hr
 1311 2543 5079 0.5007 0.4031
MDA-MB-231 PD0325901
0.12
uM
LJP6
 72
hr
 1311 2371 4935 0.4805 0.3630
MDA-MB-231 PD0325901
0.37
uM
LJP5
 72
hr
 1311 2182 5079 0.4297 0.2978
MDA-MB-231 PD0325901
0.37
uM
LJP6
 72
hr
 1311 2062 4935 0.4180 0.2668
MDA-MB-231 PD0325901
1.11
uM
LJP5
 72
hr
 1311 1708 5079 0.3360 0.1430
MDA-MB-231 PD0325901
1.11
uM
LJP6
 72
hr
 1311 1604 4935 0.3251 0.1108
MDA-MB-231 PD0325901
3.33
uM
LJP5
 72
hr
 1311 1494 5079 0.2940 0.0682
MDA-MB-231 PD0325901
3.33
uM
LJP6
 72
hr
 1311 1276 4935 0.2587 -0.0145
MDA-MB-231 PD0325901
10
uM
LJP5
 72
hr
 1311 1263 5079 0.2486 -0.0200