LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 2543 | 1700 | 5752 | 0.2955 | -0.2899 |
| SK-BR-3 | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1366 | 5418 | 0.2523 | -0.4346 |
| SK-BR-3 | Mitoxantrone | 3.33 | uM | LJP5 | 72 | hr | 2543 | 1308 | 5752 | 0.2275 | -0.4316 |
| SK-BR-3 | Mitoxantrone | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1043 | 5418 | 0.1922 | -0.5589 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP5 | 72 | hr | 2543 | 494 | 5752 | 0.0860 | -0.7514 |
| SK-BR-3 | Mitoxantrone | 10 | uM | LJP6 | 72 | hr | 2543 | 295 | 5418 | 0.0546 | -0.8617 |
| SK-BR-3 | Radicicol | 0.04 | uM | LJP5 | 72 | hr | 2543 | 3785 | 5752 | 0.6581 | 0.4017 |
| SK-BR-3 | Radicicol | 0.04 | uM | LJP6 | 72 | hr | 2543 | 3341 | 5418 | 0.6157 | 0.2801 |
| SK-BR-3 | Radicicol | 0.12 | uM | LJP5 | 72 | hr | 2543 | 2642 | 5752 | 0.4594 | 0.0330 |
| SK-BR-3 | Radicicol | 0.12 | uM | LJP6 | 72 | hr | 2543 | 2396 | 5418 | 0.4421 | -0.0543 |
| SK-BR-3 | Radicicol | 0.37 | uM | LJP5 | 72 | hr | 2543 | 2336 | 5752 | 0.4063 | -0.0696 |
| SK-BR-3 | Radicicol | 0.37 | uM | LJP6 | 72 | hr | 2543 | 2200 | 5418 | 0.4058 | -0.1258 |
| SK-BR-3 | Radicicol | 1.11 | uM | LJP5 | 72 | hr | 2543 | 2074 | 5752 | 0.3606 | -0.1591 |
| SK-BR-3 | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1944 | 5418 | 0.3590 | -0.2185 |
| SK-BR-3 | Radicicol | 3.33 | uM | LJP5 | 72 | hr | 2543 | 2231 | 5752 | 0.3879 | -0.1055 |
| SK-BR-3 | Radicicol | 3.33 | uM | LJP6 | 72 | hr | 2543 | 2083 | 5418 | 0.3849 | -0.1669 |
| SK-BR-3 | Radicicol | 10 | uM | LJP5 | 72 | hr | 2543 | 2277 | 5752 | 0.3960 | -0.0895 |
| SK-BR-3 | Radicicol | 10 | uM | LJP6 | 72 | hr | 2543 | 1979 | 5418 | 0.3658 | -0.2053 |
| SK-BR-3 | Withaferin A | 0.04 | uM | LJP5 | 72 | hr | 2543 | 5691 | 5752 | 0.9895 | 0.9820 |
| SK-BR-3 | Withaferin A | 0.04 | uM | LJP6 | 72 | hr | 2543 | 5809 | 5418 | 1.0736 | 1.1383 |
| SK-BR-3 | Withaferin A | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5358 | 5752 | 0.9316 | 0.8831 |
| SK-BR-3 | Withaferin A | 0.12 | uM | LJP6 | 72 | hr | 2543 | 4999 | 5418 | 0.9233 | 0.8602 |
| SK-BR-3 | Withaferin A | 0.37 | uM | LJP5 | 72 | hr | 2543 | 3576 | 5752 | 0.6217 | 0.3356 |
| SK-BR-3 | Withaferin A | 0.37 | uM | LJP6 | 72 | hr | 2543 | 2923 | 5418 | 0.5399 | 0.1366 |
| SK-BR-3 | Withaferin A | 1.11 | uM | LJP5 | 72 | hr | 2543 | 1858 | 5752 | 0.3231 | -0.2340 |