LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | OSI-027 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 2495 | 5418 | 0.4613 | -0.0163 |
| SK-BR-3 | OSI-027 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 2274 | 5418 | 0.4201 | -0.0974 |
| SK-BR-3 | OSI-027 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 2265 | 5418 | 0.4182 | -0.1012 |
| SK-BR-3 | OSI-027 | 10 | uM | LJP6 | 72 | hr | 2543 | 2120 | 5418 | 0.3917 | -0.1535 |
| SK-BR-3 | WYE-125132 | 0.04 | uM | LJP6 | 72 | hr | 2543 | 2445 | 5418 | 0.4512 | -0.0364 |
| SK-BR-3 | WYE-125132 | 0.12 | uM | LJP6 | 72 | hr | 2543 | 2145 | 5418 | 0.3955 | -0.1462 |
| SK-BR-3 | WYE-125132 | 0.37 | uM | LJP6 | 72 | hr | 2543 | 2034 | 5418 | 0.3754 | -0.1860 |
| SK-BR-3 | WYE-125132 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 2052 | 5418 | 0.3786 | -0.1797 |
| SK-BR-3 | WYE-125132 | 3.33 | uM | LJP6 | 72 | hr | 2543 | 1935 | 5418 | 0.3571 | -0.2223 |
| SK-BR-3 | WYE-125132 | 10 | uM | LJP6 | 72 | hr | 2543 | 1916 | 5418 | 0.3536 | -0.2294 |
| SK-BR-3 | Barasertib | 0.04 | uM | LJP5 | 72 | hr | 2543 | 2155 | 5752 | 0.3747 | -0.1313 |
| SK-BR-3 | Barasertib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 2088 | 5752 | 0.3631 | -0.1542 |
| SK-BR-3 | Barasertib | 0.37 | uM | LJP5 | 72 | hr | 2543 | 2071 | 5752 | 0.3600 | -0.1603 |
| SK-BR-3 | Barasertib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 2087 | 5752 | 0.3628 | -0.1549 |
| SK-BR-3 | Barasertib | 3.33 | uM | LJP5 | 72 | hr | 2543 | 2030 | 5752 | 0.3530 | -0.1742 |
| SK-BR-3 | Barasertib | 10 | uM | LJP5 | 72 | hr | 2543 | 2064 | 5752 | 0.3589 | -0.1625 |
| SK-BR-3 | Vemurafenib | 0.04 | uM | LJP5 | 72 | hr | 2543 | 5654 | 5752 | 0.9830 | 0.9708 |
| SK-BR-3 | Vemurafenib | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5722 | 5752 | 0.9949 | 0.9912 |
| SK-BR-3 | Vemurafenib | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5948 | 5752 | 1.0339 | 1.0572 |
| SK-BR-3 | Vemurafenib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5932 | 5752 | 1.0313 | 1.0529 |
| SK-BR-3 | Vemurafenib | 3.33 | uM | LJP5 | 72 | hr | 2543 | 5733 | 5752 | 0.9966 | 0.9939 |
| SK-BR-3 | Vemurafenib | 10 | uM | LJP5 | 72 | hr | 2543 | 5192 | 5752 | 0.9026 | 0.8331 |
| SK-BR-3 | Enzastaurin | 0.04 | uM | LJP5 | 72 | hr | 2543 | 6067 | 5752 | 1.0547 | 1.0924 |
| SK-BR-3 | Enzastaurin | 0.12 | uM | LJP5 | 72 | hr | 2543 | 5924 | 5752 | 1.0298 | 1.0505 |
| SK-BR-3 | Enzastaurin | 0.37 | uM | LJP5 | 72 | hr | 2543 | 5960 | 5752 | 1.0362 | 1.0613 |