LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 YM 201636
1.11
uM
LJP5
 72
hr
 1657 4646 5588 0.8315 0.7992
BT-20 YM 201636
0.37
uM
LJP5
 72
hr
 1657 5135 5588 0.9188 0.9047
BT-20 YM 201636
0.12
uM
LJP5
 72
hr
 1657 5446 5588 0.9746 0.9707
BT-20 YM 201636
0.04
uM
LJP5
 72
hr
 1657 5842 5588 1.0453 1.0508
MDA-MB-231 ZSTK474
10
uM
LJP6
 72
hr
 868 1948 3556 0.5476 0.4867
MDA-MB-231 ZSTK474
3.33
uM
LJP6
 72
hr
 868 2199 3556 0.6186 0.5792
MDA-MB-231 ZSTK474
1.11
uM
LJP6
 72
hr
 868 2454 3556 0.6906 0.6673
MDA-MB-231 ZSTK474
0.37
uM
LJP6
 72
hr
 868 2729 3556 0.7678 0.7564
MDA-MB-231 ZSTK474
0.12
uM
LJP6
 72
hr
 868 3136 3556 0.8821 0.8804
MDA-MB-231 ZSTK474
0.04
uM
LJP6
 72
hr
 868 3338 3556 0.9381 0.9375
MCF 10A ZSTK474
0.04
uM
LJP6
 72
hr
 513 7992 10473 0.7632 0.8793
Hs 578T ZSTK474
10
uM
LJP6
 72
hr
 929 1256 3216 0.3906 0.1829
MCF 10A ZSTK474
0.12
uM
LJP6
 72
hr
 513 5213 10473 0.4976 0.7027
MCF 10A ZSTK474
0.37
uM
LJP6
 72
hr
 513 3122 10473 0.2980 0.5140
MCF 10A ZSTK474
1.11
uM
LJP6
 72
hr
 513 2117 10473 0.2022 0.3838
MCF 10A ZSTK474
3.33
uM
LJP6
 72
hr
 513 1435 10473 0.1370 0.2649
MCF 10A ZSTK474
10
uM
LJP6
 72
hr
 513 1292 10473 0.1234 0.2346
Hs 578T ZSTK474
3.33
uM
LJP6
 72
hr
 929 1457 3216 0.4530 0.2853
Hs 578T ZSTK474
1.11
uM
LJP6
 72
hr
 929 1575 3216 0.4898 0.3426
Hs 578T ZSTK474
0.37
uM
LJP6
 72
hr
 929 1832 3216 0.5695 0.4605
Hs 578T ZSTK474
0.12
uM
LJP6
 72
hr
 929 2261 3216 0.7031 0.6429
Hs 578T ZSTK474
0.04
uM
LJP6
 72
hr
 929 2659 3216 0.8269 0.7986
SK-BR-3 ZSTK474
10
uM
LJP6
 72
hr
 1476 1506 3643 0.4146 0.0160
BT-20 ZSTK474
10
uM
LJP6
 72
hr
 1657 1543 5383 0.2861 -0.0439
BT-20 ZSTK474
3.33
uM
LJP6
 72
hr
 1657 1697 5383 0.3153 0.0134