LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T AZD-6482
10
uM
LJP5
 72
hr
 929 1568 3237 0.4845 0.3371
Hs 578T AZD-6482
3.33
uM
LJP5
 72
hr
 929 2267 3237 0.7004 0.6412
Hs 578T AZD7762
0.04
uM
LJP6
 72
hr
 929 1764 3216 0.5485 0.4302
MCF7 AZD7762
0.37
uM
LJP6
 72
hr
 1235 1544 4056 0.3810 0.1390
MCF7 AZD7762
0.12
uM
LJP6
 72
hr
 1235 1706 4056 0.4209 0.2074
MDA-MB-231 AZD7762
0.12
uM
LJP6
 72
hr
 868 1608 3556 0.4526 0.3540
Hs 578T AZD7762
0.12
uM
LJP6
 72
hr
 929 1262 3216 0.3923 0.1853
SK-BR-3 AZD7762
0.04
uM
LJP6
 72
hr
 1476 1505 3643 0.4110 0.0064
SK-BR-3 AZD7762
0.37
uM
LJP6
 72
hr
 1476 1283 3643 0.3493 -0.1140
MCF7 AZD7762
0.04
uM
LJP6
 72
hr
 1235 1904 4056 0.4696 0.2871
Hs 578T AZD7762
0.37
uM
LJP6
 72
hr
 929 1146 3216 0.3564 0.1243
MDA-MB-231 AZD7762
0.37
uM
LJP6
 72
hr
 868 1351 3556 0.3800 0.2425
SK-BR-3 AZD7762
0.12
uM
LJP6
 72
hr
 1476 1351 3643 0.3693 -0.0732
MCF7 AZD7762
3.33
uM
LJP6
 72
hr
 1235 1057 4056 0.2607 -0.0870
BT-20 AZD7762
0.04
uM
LJP6
 72
hr
 1657 5881 5383 1.0932 1.1076
MCF7 AZD7762
10
uM
LJP6
 72
hr
 1235 765 4056 0.1887 -0.2437
MDA-MB-231 AZD7762
3.33
uM
LJP6
 72
hr
 868 683 3556 0.1921 -0.1122
MDA-MB-231 AZD7762
1.11
uM
LJP6
 72
hr
 868 852 3556 0.2399 -0.0093
SK-BR-3 AZD7762
1.11
uM
LJP6
 72
hr
 1476 1052 3643 0.2870 -0.2365
BT-20 AZD7762
3.33
uM
LJP6
 72
hr
 1657 1552 5383 0.2891 -0.0378
MCF 10A AZD7762
3.33
uM
LJP6
 72
hr
 513 936 10473 0.0894 0.1480
BT-20 AZD7762
0.37
uM
LJP6
 72
hr
 1657 4158 5383 0.7729 0.7188
MDA-MB-231 AZD7762
0.04
uM
LJP6
 72
hr
 868 2059 3556 0.5781 0.5263
MDA-MB-231 AZD7762
10
uM
LJP6
 72
hr
 868 633 3556 0.1784 -0.1438
BT-20 AZD7762
0.12
uM
LJP6
 72
hr
 1657 5352 5383 0.9954 0.9950