LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 Mitoxantrone
3.33
uM
LJP5
72
hr
1657 1389 5588 0.2489 -0.0974
BT-20 Mitoxantrone
3.33
uM
LJP6
72
hr
1657 1288 5383 0.2391 -0.1397
SK-BR-3 WZ3105
3.33
uM
LJP5
72
hr
1476 1189 3772 0.3153 -0.1480
MCF7 HG-5-113-01
3.33
uM
LJP5
72
hr
1235 1371 4267 0.3216 0.0600
MCF 10A XMD11-50
3.33
uM
LJP6
72
hr
513 1574 10473 0.1503 0.2937
BT-20 Seliciclib
3.33
uM
LJP5
72
hr
1657 4547 5588 0.8139 0.7783
BT-20 Radicicol
3.33
uM
LJP5
72
hr
1657 1834 5588 0.3284 0.0596
BT-20 Radicicol
3.33
uM
LJP6
72
hr
1657 1848 5383 0.3434 0.0660
SK-BR-3 Seliciclib
3.33
uM
LJP5
72
hr
1476 2912 3772 0.7723 0.6524
MDA-MB-231 BI-2536
3.33
uM
LJP6
72
hr
868 1170 3556 0.3303 0.1580
MCF 10A R406
3.33
uM
LJP6
72
hr
513 5300 10473 0.5062 0.7085
MCF7 XMD11-50
3.33
uM
LJP6
72
hr
1235 1660 4056 0.4094 0.1880
MDA-MB-231 Withaferin A
3.33
uM
LJP6
72
hr
868 675 3556 0.1899 -0.1183
BT-20 Withaferin A
3.33
uM
LJP5
72
hr
1657 907 5588 0.1626 -0.2916
BT-20 Withaferin A
3.33
uM
LJP6
72
hr
1657 901 5383 0.1669 -0.3048