LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T HG-6-64-01
0.04
uM
LJP6
 72
hr
 929 3750 3216 1.1660 1.1789
Hs 578T Alvocidib
0.04
uM
LJP6
 72
hr
 929 2245 3216 0.6982 0.6365
Hs 578T Alvocidib
3.33
uM
LJP6
 72
hr
 929 751 3216 0.2335 -0.1123
Hs 578T Alvocidib
0.12
uM
LJP6
 72
hr
 929 852 3216 0.2649 -0.0482
Hs 578T Alvocidib
0.37
uM
LJP6
 72
hr
 929 734 3216 0.2284 -0.1247
Hs 578T AT-7519
0.04
uM
LJP6
 72
hr
 929 3200 3216 0.9948 0.9941
Hs 578T AZD7762
0.37
uM
LJP6
 72
hr
 929 1146 3216 0.3564 0.1243
Hs 578T GW843682X
0.12
uM
LJP6
 72
hr
 929 2312 3216 0.7193 0.6634
Hs 578T GW843682X
0.37
uM
LJP6
 72
hr
 929 1074 3216 0.3341 0.0844
Hs 578T AT-7519
0.12
uM
LJP6
 72
hr
 929 2782 3216 0.8649 0.8442
Hs 578T AT-7519
0.37
uM
LJP6
 72
hr
 929 967 3216 0.3006 0.0222
Hs 578T AT-7519
3.33
uM
LJP6
 72
hr
 929 737 3216 0.2291 -0.1227
Hs 578T AT-7519
10
uM
LJP6
 72
hr
 929 616 3216 0.1917 -0.2056
Hs 578T AZD7762
1.11
uM
LJP6
 72
hr
 929 1015 3216 0.3157 0.0506
Hs 578T AZD7762
3.33
uM
LJP6
 72
hr
 929 853 3216 0.2653 -0.0466
Hs 578T AZD8055
0.04
uM
LJP6
 72
hr
 929 1457 3216 0.4532 0.2857
Hs 578T AZD8055
0.12
uM
LJP6
 72
hr
 929 1326 3216 0.4123 0.2195
Hs 578T AZD8055
3.33
uM
LJP6
 72
hr
 929 1264 3216 0.3929 0.1870
Hs 578T AZD8055
10
uM
LJP6
 72
hr
 929 1012 3216 0.3148 0.0486
Hs 578T Sorafenib
0.12
uM
LJP6
 72
hr
 929 3812 3216 1.1852 1.1991
Hs 578T Sorafenib
0.37
uM
LJP6
 72
hr
 929 3923 3216 1.2199 1.2347
Hs 578T Alvocidib
10
uM
LJP6
 72
hr
 929 814 3216 0.2532 -0.0719
Hs 578T HG-5-88-01
0.12
uM
LJP6
 72
hr
 929 3045 3216 0.9467 0.9397
Hs 578T JW-7-24-1
0.12
uM
LJP6
 72
hr
 929 2955 3216 0.9188 0.9077
Hs 578T JW-7-24-1
0.04
uM
LJP6
 72
hr
 929 3051 3216 0.9484 0.9415