LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A AZD 5438
0.12
uM
LJP6
 72
hr
 513 5533 10473 0.5284 0.7268
MCF 10A AZD 5438
0.37
uM
LJP6
 72
hr
 513 1767 10473 0.1688 0.3277
MCF 10A AZD 5438
1.11
uM
LJP6
 72
hr
 513 579 10473 0.0553 0.0279
MCF 10A AZD 5438
3.33
uM
LJP6
 72
hr
 513 704 10473 0.0672 0.0750
MCF 10A AZD 5438
10
uM
LJP6
 72
hr
 513 576 10473 0.0550 0.0269
MCF 10A GSK1059615
0.04
uM
LJP6
 72
hr
 513 8625 10473 0.8236 0.9126
MCF 10A GSK1059615
0.12
uM
LJP6
 72
hr
 513 5019 10473 0.4788 0.6853
MCF 10A GSK1059615
0.37
uM
LJP6
 72
hr
 513 2001 10473 0.1911 0.3664
MCF 10A GSK1059615
1.11
uM
LJP6
 72
hr
 513 778 10473 0.0743 0.0995
MCF 10A GSK1059615
3.33
uM
LJP6
 72
hr
 513 459 10473 0.0438 -0.0260
MCF 10A GSK1059615
10
uM
LJP6
 72
hr
 513 317 10473 0.0302 -0.1063
MCF 10A CHIR-99021
0.04
uM
LJP6
 72
hr
 513 9979 10473 0.9528 0.9776
MCF 10A CHIR-99021
0.12
uM
LJP6
 72
hr
 513 9570 10473 0.9138 0.9587
MCF 10A CHIR-99021
0.37
uM
LJP6
 72
hr
 513 8716 10473 0.8322 0.9173
MCF 10A CHIR-99021
1.11
uM
LJP6
 72
hr
 513 6771 10473 0.6464 0.8082
MCF 10A CHIR-99021
3.33
uM
LJP6
 72
hr
 513 6115 10473 0.5838 0.7670
MCF 10A CHIR-99021
10
uM
LJP6
 72
hr
 513 4632 10473 0.4423 0.6542
MCF 10A Linifanib
0.04
uM
LJP6
 72
hr
 513 11575 10473 1.1054 1.0465
MCF 10A Linifanib
0.12
uM
LJP6
 72
hr
 513 11112 10473 1.0611 1.0274
MCF 10A Linifanib
0.37
uM
LJP6
 72
hr
 513 10979 10473 1.0485 1.0218
MCF 10A Linifanib
1.11
uM
LJP6
 72
hr
 513 10826 10473 1.0337 1.0152
MCF 10A Linifanib
3.33
uM
LJP6
 72
hr
 513 9782 10473 0.9340 0.9688
MCF 10A Linifanib
10
uM
LJP6
 72
hr
 513 2516 10473 0.2403 0.4388
MCF 10A Mitoxantrone
0.04
uM
LJP6
 72
hr
 513 907 10473 0.0867 0.1399
MCF 10A Mitoxantrone
0.12
uM
LJP6
 72
hr
 513 690 10473 0.0659 0.0694