LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A GW843682X
0.12
uM
LJP6
 72
hr
 513 6501 10473 0.6206 0.7920
MCF 10A GW843682X
0.37
uM
LJP6
 72
hr
 513 2003 10473 0.1913 0.3672
MCF 10A GW843682X
3.33
uM
LJP6
 72
hr
 513 701 10473 0.0669 0.0735
MCF 10A GW843682X
10
uM
LJP6
 72
hr
 513 701 10473 0.0669 0.0723
MCF 10A HG-5-113-01
1.11
uM
LJP5
 72
hr
 513 4879 10362 0.4707 0.6805
MCF 10A HG-5-113-01
3.33
uM
LJP5
 72
hr
 513 1445 10362 0.1394 0.2695
MCF 10A HG-5-88-01
0.04
uM
LJP6
 72
hr
 513 7496 10473 0.7158 0.8520
MCF 10A HG-5-88-01
0.12
uM
LJP6
 72
hr
 513 6249 10473 0.5967 0.7760
MCF 10A HG-5-88-01
3.33
uM
LJP6
 72
hr
 513 2412 10473 0.2304 0.4263
MCF 10A HG-5-88-01
10
uM
LJP6
 72
hr
 513 1800 10473 0.1720 0.3325
MCF 10A HG-6-64-01
0.12
uM
LJP6
 72
hr
 513 10535 10473 1.0061 1.0025
MCF 10A HG-6-64-01
0.37
uM
LJP6
 72
hr
 513 9226 10473 0.8810 0.9426
MCF 10A Seliciclib
0.04
uM
LJP5
 72
hr
 513 10313 10362 0.9953 0.9978
MCF 10A Seliciclib
0.12
uM
LJP5
 72
hr
 513 9976 10362 0.9629 0.9824
MCF 10A Seliciclib
1.11
uM
LJP5
 72
hr
 513 9610 10362 0.9278 0.9654
MCF 10A Seliciclib
3.33
uM
LJP5
 72
hr
 513 8627 10362 0.8327 0.9169
MCF 10A AT-7519
0.12
uM
LJP6
 72
hr
 513 7852 10473 0.7495 0.8710
MCF 10A AT-7519
0.37
uM
LJP6
 72
hr
 513 995 10473 0.0950 0.1636
MCF 10A AT-7519
3.33
uM
LJP6
 72
hr
 513 665 10473 0.0636 0.0613
MCF 10A AT-7519
10
uM
LJP6
 72
hr
 513 482 10473 0.0461 -0.0150
MCF 10A AZD7762
1.11
uM
LJP6
 72
hr
 513 1722 10473 0.1645 0.3189
MCF 10A AZD7762
3.33
uM
LJP6
 72
hr
 513 936 10473 0.0894 0.1480
MCF 10A AZD8055
0.04
uM
LJP6
 72
hr
 513 2503 10473 0.2388 0.4339
MCF 10A Neratinib
0.37
uM
LJP5
 72
hr
 513 778 10362 0.0751 0.1006
MCF 10A Neratinib
0.12
uM
LJP5
 72
hr
 513 766 10362 0.0740 0.0969