LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Tozasertib
3.33
uM
LJP5
 72
hr
 1235 1433 4267 0.3365 0.0872
MCF7 Seliciclib
0.37
uM
LJP5
 72
hr
 1235 3789 4267 0.8882 0.8715
MCF7 CGP60474
0.04
uM
LJP5
 72
hr
 1235 4211 4267 0.9887 0.9876
MCF7 CGP60474
0.37
uM
LJP5
 72
hr
 1235 777 4267 0.1822 -0.2286
MCF7 CP466722
0.04
uM
LJP5
 72
hr
 1235 4851 4267 1.1371 1.1490
MCF7 CP466722
0.12
uM
LJP5
 72
hr
 1235 4537 4267 1.0633 1.0695
MCF7 CP466722
0.37
uM
LJP5
 72
hr
 1235 4829 4267 1.1306 1.1406
MCF7 CP466722
1.11
uM
LJP5
 72
hr
 1235 4687 4267 1.0985 1.1079
MCF7 CP466722
3.33
uM
LJP5
 72
hr
 1235 4230 4267 0.9910 0.9888
MCF7 CP466722
10
uM
LJP5
 72
hr
 1235 1972 4267 0.4623 0.2987
MCF7 CP724714
0.04
uM
LJP5
 72
hr
 1235 3247 4267 0.7619 0.7178
MCF7 CP724714
0.12
uM
LJP5
 72
hr
 1235 3363 4267 0.7888 0.7515
MCF7 CP724714
0.37
uM
LJP5
 72
hr
 1235 3410 4267 0.7997 0.7651
MCF7 CP724714
1.11
uM
LJP5
 72
hr
 1235 3304 4267 0.7743 0.7334
MCF7 CP724714
3.33
uM
LJP5
 72
hr
 1235 3278 4267 0.7684 0.7259
MCF7 CP724714
10
uM
LJP5
 72
hr
 1235 2110 4267 0.4950 0.3495
MCF7 HG-5-113-01
10
uM
LJP5
 72
hr
 1235 883 4267 0.2073 -0.1712
MCF7 Neratinib
0.37
uM
LJP5
 72
hr
 1235 2689 4267 0.6306 0.5451
MCF7 Neratinib
1.11
uM
LJP5
 72
hr
 1235 2436 4267 0.5710 0.4617
MCF7 Neratinib
10
uM
LJP5
 72
hr
 1235 1169 4267 0.2741 -0.0312
MCF7 Dasatinib
0.04
uM
LJP5
 72
hr
 1235 2621 4267 0.6157 0.5235
MCF7 Seliciclib
10
uM
LJP5
 72
hr
 1235 706 4267 0.1657 -0.2687
MCF7 Dasatinib
10
uM
LJP5
 72
hr
 1235 918 4267 0.2150 -0.1538
MCF7 Crizotinib
0.12
uM
LJP5
 72
hr
 1235 3061 4267 0.7180 0.6618
MCF7 Crizotinib
0.04
uM
LJP5
 72
hr
 1235 3325 4267 0.7794 0.7387